Design,Synthesis and Biological Evaluation of Novel Limonin Derivatives

来源 :全国药物化学学术会议暨第四届中英药物化学学术会议 | 被引量 : 0次 | 上传用户:wudajiang1213
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  Limonoids are typical secondary metabolites,abundant in citrus fruit and other plants found in the Rutaceae and Meliaceae families.Currently limonoids are under investigation for various therapeutic effects such as antitumor,anti-inflammatory,analgesic,antibacteria,antimalaria and antifeedant.However,these active substance present poor water solubility and low bioavailability,which greatly limit their clinical application.
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