anti-cancer相关论文
Genipin and geniposide from Gardenia jasminoides:An overview of their anti-cancer and other pharmaco
Genipin and geniposide are iridoids from the fruits of Gardenia jasminoides.Both compounds have a methyl acetate(-COOCH3......
Encoded by PTPN11,the SHP2(Src homology-2 domain-containing protein tyrosine phosphatase-2)is widely recognized as a car......
Mitochondrial shape rapidly changes by dynamic balance of fusion and fission to adjust to constantly changing energy dem......
Inhibition of human epidermal growth factor receptor 2 mediated cell signaling pathway is an important therapeutic strat......
Proteomic and bioinformatic analyses of possible target-related proteins of gambogic acid in human b
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Organometallic drugs have often occupied a difficult niche in terms of therapeutic value.Bioactive metal containing comp......
Verbascoside(VB),a major bioactive constituent of the Tsoong herb,has attracted a great deal of attention due to its pha......
PAMAM dendrimer is a highly effective nanocarrier(Generally refers to G3-G7).But PAMAM dendrimer without modification ma......
Development of chitosan-based nanoparticles for improving anti-cancer effects and bioavailability of
Mifepristone(RU486,MIF)acted as the progesterone receptor(PR)modulator has been widely used for emergency contraception ......
Currently,biodegradable nanoparticles derived from natural compounds are widely used in the biomedical field[1].In our p......
Theabrownin promote apoptosis and autophagy of hepatocellular carcinoma via b-catenin and MEK/ERK pa
Objective Hepatocellular carcinoma(HCC)is the primary malignant tumor in the liver.Liver cancer is the third common caus......
Checkpoint kinase 1(Chk1) is a Ser/Thr kinase that is involved in mediating the cellular response to DNA-damage.Inhibiti......
Tanshinone IIA(Tan IIA)the major component of traditional Chinese medicinal herb Danshen,give its anti-cancer effects pa......
The Aurora kinases are a family of serine/threonine kinases that interact with components of the mitotic apparatus and s......
Small-Molecule-Induced Transcription Repression through Interfering with NM23-H2 Binding to G-quadru
NM23-H2 protein is identified as a transcriptional factor of the important oncogene c-myc,that can bind specifically to ......
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Synthesis and Biological Evaluation of Novel Berberine Derivatives as Potent Inhibitors against IFN-
To explore down-regulating IDO1 expression ability of small-molecule inhibitors in tumor cells,twenty-five novel berberi......
Checkpoint kinase 1(Chk1)represents an attractive target for anticancer therapy and the development of small molecule Ch......
Objective To assay the anticancer actions of extracts of yacon leaves mainly composed of sesquiterpene lactone with H22 ......
Aims: In this study, the anti-cancer mechanisms of moscatilin(MT-4), have been examined in cisplatin-sensitive ovarian c......
Molybdo-complexes with Polyhydroxy phenols, their structures and activities against human cancer cel
Nature has chosen the molybdenum as active center in some oxotransferase enzymes such asXanthine oxidase in which molybd......
Since the discovery of anti-cancer agent cisplatin,various metal-based complexes have been subsequently proven to displa......
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Glutathione/pH Responsive Sulfur Dioxide Gas Generation Nanoplatform for Macrophage Polarization and
As a well-known toxic air pollutant,SO2 displays broad and complex toxicological effects,including oxidative damage,deox......
8-Hydroxyquinoline is an efficient bidentate ligand(L)of metal ions(M)such as AgⅠ,CdⅡ,CoⅡ,CuⅡ,FeⅢ,GaⅢ,LuⅢ,MnⅡ,Ni......
The genus Isodon has attracted much attention as a prolific source of ent-kauranoids with diverse structures and biologi......
Peptide tyrosine-tyrosine combined with its receptors exhibits an anti-cancer potential in pancreati
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Pharmacological and therapeutic properties of the Red Clover (Trifo-lium pratense L.):an overview of
OBJECTIVE:To review beneficial effects of red clo-ver (Trifolium pratense L.) on biological processes.METHODS:A systemat......
Paclitaxel-loaded and folic acid-modified PLGA nanomedicine with glutathione response for the treatm
Targeted delivery and smart response of nanomedicine hold great promise for improving the therapeutic efficacy and allev......
Tumor-associated carbohydrate antigens(TACAs)are regarded as important targets for vaccine development.Vaccines base......
Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothe
Angiogenesis plays an essential role in many physiological and pathological processes.Quercetin,a plant pigment and ......
Objective Bacillus strains are well known for their natural bioactive products that have antimicrobial and/or anti-cance......
Due to the nontoxicity and efficient anti-cancer activity, more and more attention has been paid to N-glycoside compound......
核心蛋白聚糖(decorin,DCN)是一种与胶原纤维相关的蛋白聚糖,广泛存在于细胞外基质中.DCN可通过多种途经发挥抗纤维化、抗肿瘤等作......
Therapeutic role of Ricinus communis L.and its bioactive compounds in disease prevention and treatme
Ricinus communis L.(R.communis),commonly known as castor oil plant,is used as a traditional natural remedy or folkloric ......
Objective: To investigate the cytotoxic, antioxidant and antibacterial activities of ethanolic and aqueous crude extract......
Objective: To study the anti-tumor activities of furanodiene (C15H20O), a primary sesquiterpene compound isolated from t......
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硫氧还蛋白还原酶(TrxR)是哺乳动物细胞内负责清除过量活性氧族(ROS)的重要酶类.本研究的目的是探究ROS在TrxR抑制剂乙烷硒啉抗肿......
异戊烯基黄酮类化合物主要分布在豆科和桑科植物中,具有多种生物活性.我们之前报道了一个从甘草中得到的异戊烯基异黄酮isoangusto......
拓扑异构酶Ⅰ和拓扑异构酶Ⅱ双重抑制剂因为具有双靶点,在提高抗增值活性的同时可以降低毒副作用.作者设计并合成了28个茚[1,2-b]......
Photodynamic therapy (PDT),based on the photoactivation of photosensitizers (PSs),has become a well-studied therapy for ......
活性氧物种(ROS)由于其在生物体内的“双刃剑”作用受到越来越多的关注.ROS在低浓度下能够促进细胞生长,而在高浓度下会诱导细胞凋......
Sesamum indicum (sesame) enhances NK anti-cancer activity, modulates Th1/Th2 balance, and suppresses
Objective: To evaluate the potential immunomodulatory effects of an aqueous extract of Sesamum indicum seeds with regard......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Synthesis, Crystal Structure and in vitro Anticancer Studies of 1,2-Bis-benzimidazole-phenyl Copper(
本文通过对荣华二采区10...
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
纺锤体驱动蛋白(kinesin spindle protein,KSP)抑制药是抗肿瘤药物研究的一个重要方向,已有数个KSP抑制药进入临床研究。ATP竞争性......
