【摘 要】
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Nature has chosen the molybdenum as active center in some oxotransferase enzymes such asXanthine oxidase in which molybdenum catalyzes electrons and oxygen atoms transfer and theMo=O unit play “specta
【机 构】
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Department of Chemistry, Capital Normal University, Beijing 100037, P. R. China
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Nature has chosen the molybdenum as active center in some oxotransferase enzymes such asXanthine oxidase in which molybdenum catalyzes electrons and oxygen atoms transfer and theMo=O unit play “spectator” role in the transfer process.Polyhydroxy phenols and their derivativeshave been a hot topic because of its potential anti-cancer activities.We have reported someprominent chemotherapeutic molybdenum complexes,and now we are interested in therelationship between their structures and anti-cancer activities,especially the effects of the numberof the ligands and the size of polyhydroxyl aromatic rings coordinated with Mo.The reaction of (NH4)2Mo2O7·2H2O with catechol and 2,3-dihydroxynaphthalene,respectively,inthe mix-solvent of MeCN/EtOH/amine have resulted in four molybdenum(vi) complexes,(enH2)[MoO3(C6H4O2)(en)] (1),(tnH2)[MoO3(C6H4O2)(tn)] (2),(enH)2[MoO2(C6H4O2)2](en)0.5(3),and (HNEt3)2[MoO2(C10H8O2)2] (4).
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