MDSCs相关论文
目的:研究中药复方SC01的物质基础,确定其质量标志物,探究复方SC01对骨髓来源免疫抑制细胞(myeloid derived suppress cells,MDSCs)......
研究背景及目的:非小细胞肺癌(Non-small cell lung cancer,NSCLC)是肺癌最常见的组织学亚型,占所有肺癌病例的85%以上,晚期NSCLC的......
研究背景和目的:髓系来源的抑制细胞(MDSCs)是未分化成熟的、异质性的髓样细胞群体,具有免疫抑制功能,被证实在肿瘤和慢性炎症中大量......
第一部分 制备联合负载盐酸吉西他滨与顺铂的静电纺丝纳米缓释材料并探究其在体外的药物释放行为[目的]制备联合负载盐酸吉西他滨......
乳腺癌、肝癌和结肠癌在我国癌症的发病率和死亡率都在前五位,需要寻找有效的治疗和延长患者生存方法。慢性炎症在乳腺癌、肝癌和......
第一部分骨髓来源抑制性细胞在实验性自身免疫性心肌炎小鼠中的表达规律目的探究骨髓来源抑制性细胞(Myeloid-derived suppressor c......
SUMO(small ubiquitin-like modifier)化修饰通过影响底物蛋白质的功能参与调控机体多种生理与病理过程。近年来的研究发现SUMO化修......
目的青蒿素(Artemisinin,ART)及其衍生物是一类含有过氧基团的倍半萜内酯类药物,现已成为国际社会上普遍认可并投入使用的抗疟疾首选......
目的 探讨瘦素(leptin)与MDSCs在病毒性心肌炎(viral myocarditis,VMC)小鼠发生中的作用.方法 首先诱导VMC模型,然后实验分为对照......
目的 小细胞肺癌(Small cell lung cancer,SCLC)发生和进展机制复杂,临床治疗缺乏突破,急需寻找新标志物来预测和改善小细胞肺癌的......
The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated f
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Effects of Anesthetic Technique and Surgery on Myeloid-Derived Suppressor Cells and Prognosis in Wom
目的 Myeloid-derived suppressor cells(MDSCs)are highly immunosuppressive myeloid cells,closely linked with tumor staging......
Small extracellular vesicles derived from esophageal squamous cell carcinoma promote immunosuppressi
Objective Radiation therapy is effective in achieving local control in esophageal squamous cell carcinoma(ESCC),yet ther......
Enhanced circulating ILC2s and MDSCs in patients with lung cancer accompanied by a predominant Th2 p
BACKGROUND: Group 2 innate lymphoid cells (ILC2s) were shown to be involved in the initiation and coordination of Th2-ty......
Together, Elevated Alternatively Activated Macrophages,Myeloid-Derived Suppressor Cells and Th2 Cell
Background: During carcinogenesis, myeloid derived suppressor cells (MDSCs) and M2 macrophages, as major host components......
Objective Human colorectal cancer(CRC)is a major killer in the world,responsible for~655,000 deaths globally each year.C......
背景:髓性抑制细胞(myeloid-derived suppressor cells,MDSCs)是由骨髓来源的巨噬细胞、中性粒细胞和树突状细胞等不成熟的前体细......
目的:肿瘤发展与慢性炎症尤其是IL-23/IL-17通路相关。然而,人大肠癌组织IL-17的来源及其分泌细胞促进肿瘤进展的机制尚不清楚。方法......
Group 2 innate lymphoid cells (ILC2s) were shown to be involved in the initiation and coordination of Th2-type immune re......
目的:机体的免疫系统在口腔鳞状细胞癌发生发展中发挥重要的作用。目前单一的免疫治疗药物对于患者抑制肿瘤的效率并不高,因此寻找可......
Peritoneal metastasis of colorectal cancer is a major clinical issue and results in poor prognosis for patients after su......
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The emergence and clinical application of immunotherapy is considered a promising breakthrough in cancer treatment. Acco......
背景与目的: 肿瘤微环境是肿瘤发展演变的重要影响因素,其中骨髓源性抑制细胞MDSCs是肿瘤微环境的重要组成部分,MDSCs及相关炎症因......
银屑病是一种常见的难治性皮肤病,以过度激活的T细胞产生的异常免疫应答为主要特征。在机体免疫系统内,免疫抑制性细胞主要包括髓......
Lung cancer has the highest incidence and mortality rate among all cancers.It is also one of the most threatening malign......
STAT4 Knockout Protects LPS-induced Lung Injury by Increasing of MDSC and Promoting of Macrophage Di
The disruption of signal transducer and activator of transcription 4 (STAT4) signal can inhibit the inflammation and......
研究背景:细胞核内的HMGB1是一种DNA结合蛋白,但细胞外的HMGB1可作为一种警报素刺激炎症反应、调节免疫应答;髓系来源抑制细胞(MD......
MDSCs were originally described as a heterogeneous population of immature cells derived from myeloid progenitors wit......
目的探讨并分析正常人对照组及慢性乙型肝炎患者外周血中MDSCs含量与病毒载体、疾病预后的关系。方法分别用流式细胞仪检测健康人......
肿瘤微环境,即肿瘤细胞产生和生活的内环境.越来越多的证据显示,肿瘤微环境中的免疫细胞在促进肿瘤的发生及恶性进展中扮演着重要......
研究背景:髓源性抑制细胞(Myeloid-derived suppressor cells,MDSCs)是一类髓系起源的异质性群体,包含髓样前体细胞和不成熟髓样细胞......
目的:研究乙酰化酶P300介导的CCAAT/增强子结合蛋白β(CCAAT/enhancer-binding protein beta,C/EBPβ)乙酰化修饰对髓源性抑制细胞......
[目的]第一部分:髓源抑制性细胞(MDSCs)是一组具有强免疫抑制功能的细胞,在人类,MDSCs的表型为HLA-DR(-)CD33(+);而作为一类重要的......
髓源抑制性细胞(MDSCs)是来源于髓系的一群由异质性细胞组成的细胞群,它们是生物体内存在的典型的抑制性的免疫细胞,能够通过抑制T......
目的:初步探讨长链非编码RNA Snhg6(long noncoding RNA Snhg6,lncRNA Snhg6)对髓源性抑制细胞(myeloid-derived suppressor cells,MD......
髓系来源性抑制细胞(MDSCs)是来自髓系的具有异质性未分化成熟的细胞群,首次发现于肿瘤患者外周血循环中。目前,MDSCs在各种严重人......
目的研究荷瘤小鼠脾脏中髓源抑制细胞(myeloid derived suppresser-cell,MDSCs)的分选与鉴定方法。方法常规培养小鼠肾癌细胞(Renc......
银屑病是一种常见的难治性皮肤病,以过度激活的T细胞产生的异常免疫应答为主要特征.在机体免疫系统内,免疫抑制性细胞主要包括髓源......