EXOSOMES相关论文
Exosome-mediated cell-cell communication within pancreatic cancer tumor microenvironment: a narrativ
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细胞外囊泡（EV）是大多数真核细胞分泌的纳米级颗粒，在细胞间的物质转运和信息传递中扮演重要角色，参与炎症、血管生成、抗原呈递、细胞......
目的:探讨耐力训练对帕金森病(Parkinson disease，PD)模型小鼠的保护作用以及通过AMPK/mTOR通路对自噬和外泌体途径的影响。方法:选......
肝衰竭是由于各种致病因素造成肝细胞大量坏死，超过肝脏的自我修复能力，是一种严重的临床综合征，病情进展迅速，病死率高。肝移植是肝衰......
Blood exosomes, which are extracellular vesicles secreted by living cells into the circulating blood, are regarded as a ......
间充质干细胞作为一种具有免疫调节功能的成体干细胞，在肺部疾病中有很高的应用价值。随着对其作用机制研究的深入，在间充质干细胞与......
Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of e
The lung is one of the most common sites for cancer metastasis.Collagens in the lung pro-vide a permissive microenvironm......
肝脏是人体重要的器官之一,具有代谢、糖原储存、药物解毒、胆汁分泌等广泛的功能。肝功能对于体内平衡至关重要,手术,创伤,药物等......
目的:探讨急性呼吸窘迫综合征（ARDS）患者肺泡灌洗液（BALF）和血浆中外泌体含量与肺损伤严重程度及其预后的相关性。方法:选取从2020年8......
目的:观察脐带间充质干细胞分泌的外泌体对骨性关节炎模型大鼠疼痛行为、软骨修复及背根神经节(DRG)中转录激活因子3(ATF-3)及生长......
目的:评价肝缺血再灌注大鼠外泌体对小胶质细胞焦亡的影响。方法:清洁级健康雄性SD大鼠20只，2~3周龄，体重20~50 g，采用随机数字表法分......
目的:建立人真皮成纤维细胞（HDF）高糖老化模型，探讨人蜕膜间充质干细胞（dMSC）来源外泌体对高糖老化HDF增殖、迁移、凋亡的影响及其可能......
Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and o......
Inflammatory responses,including glial cell activation and peripheral immune cell infiltration,are involved in the patho......
Astrocytes protect neurons by modulating neuronal function and survival.Astrocytes support neurons in several ways.They ......
目的 分析急性脑梗死患者血清外泌体差异基因表达谱,以期阐明脑梗死损伤相关的基因表达变化和潜在血清标志物.方法 第Ⅰ期研究纳入......
Multiplexed Biosensing Diagnostic Platforms Detecting Autoantibodies to Tumor-Associated Antigens fr
Colorectal cancer(CRC)is the second leading cause of cancer-related death worldwide.The five-year sur-vival rate of CRC ......
Rapid metastasis to vital organs such as the lung,liver,and brain is responsible for the vast majority of pancreatic can......
Exosomal lncRNA FOXD3-AS1 upregulates ELAVL1 expression and activates PI3K/Akt pathway to enhance lu
Long non-coding RNA (lncRNA) FOXD3-AS1 expression is upregulated in lung cancer;however,its effect and mechanism on 5-fl......
炎症性肠病（IBD）是一种慢性复发性胃肠道炎症性疾病。外泌体作为人体生理和病理过程中重要的纳米级调控因子，被证实参与了IBD的发生发......
目的:研究致敏性CD4n + T细胞在心肌梗死（心梗）后心肌重构中的作用。n 方法:①体外实验：提取原代小鼠脾脏CD4n + T细胞......
支气管肺发育不良(bronchopulmonary dysplasia，BPD)是早产儿常见的慢性呼吸系统疾病，其病死率高、存活患儿远期预后差，目前尚缺乏有......
间充质干细胞（mesenchymal stem cells,MSCs）作为一种具有多向分化潜能的细胞,可以分化脂肪细胞,成骨细胞以及神经细胞等。有研究已......
Exosomes derived from 3D-cultured MSCs improve therapeutic effects in periodontitis and experimental
Although mesenchymal stem cell-derived exosomes (MSC-exos) have been shown to have therapeutic effects in experimental p......
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in molecular trafficking,int......
Protective effect of mesenchymal stem cell-derived exosomal treatment of hippocampal neurons against
BACKGROUND: Individuals who survive a cardiac arrest often sustain cognitive impairments due to ischemia-reperfusion inj......
目的:探讨大鼠骨髓间充质干细胞（BMSCs）来源的外泌体对髁突软骨细胞蛋白多糖含量表达的影响，为骨关节病的防治提供基础。方法:研究时......
Spinal cord injury (SCI) research is a very complex field lending to why reviews of SCI literatures can be beneficial to......
增生性瘢痕(HS)存在疼痛、瘙痒、畸形及功能障碍等问题，严重影响人们的心理健康、降低生活质量。目前关于HS的治疗方案种类繁多，但疗......
目的:探讨人羊膜上皮细胞外泌体（hAEC-Exo）对高糖环境下HaCaT增殖和迁移的作用及其相关机制。方法:采用实验研究方法。取2019年1—6......
Profile of the RNA in exosomes from astrocytes and microglia using deep sequencing: implications for
Glial cells play an important role in signal transduction, energy metabolism, extracellular ion homeostasis and neuropro......
Extracellular vesicles have been identified as pivotal mediators of intercellular communication with critical roles in p......
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm,released upon fusion of multivesicular bodies wi......
Natural extracellular vesicles(EVs)play important roles in many life processes such as in the intermolecular transfer of......
Mesenchymal stem cell-derived exosomal miR-21a-5p promotes M2 macrophage polarization and reduces ma
Atherosclerosis(AS)is the main pathological basis for ischemic cardiovascular and cerebrovascu-lar diseases.Mesenchymal ......
miR-100-5p in human umbilical cord mesenchymal stem cell-derived exosomes mediates eosinophilic infl
Exosomes derived from human umbilical cord mesenchymal stem cells(hUCMSC-Ex)play impor-tant roles in immune and inflamma......
The use of hydrogel-delivered extracellular vesicles rin recovery of motor function in stroke: a tes
Neural tissue engineering, nanotechnology and neuroregeneration are diverse biomedical disciplines that have been workin......
Exosomes are cell-derived vesicles that are secreted by many eukaryotic cells.It has recently attracted attention as veh......
In recent years,exosome has attracted extensive attention of researchers.Result from the studies found that it is relate......
Exosomes secreted by human-induced pluripotent stem cell-derivedmesenchymal stem cells repair osteoc
Purpose: The purpose of this study was to investigate the chondrogenic features of exosomes secreted by human-induced pl......
Exosomes derived from lung cancer adenocarcinoma cells containing EGFR E746-A750 deletion mutation i
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Chitosan wound dressings incorporating exosomes derived from miR-126-overexpressing synovium mesench
There is a need to find better strategies to promote wound healing, especially of chronic wounds which remain a challeng......
Objective Immunotherapy,principally represented by programmed death-1/programmed death ligand-1(PD-1/PD-L1)inhibitors,ha......
In situ implantation of photoactive hydrogel with exosomes secreted by human-induced pluripotent ste
Purpose: To investigate cartilage regeneration effects of exosomes secreted by human-induced pluripotent stem cell-deriv......
Exosomes secreted from human-induced pluripotent stem cellderived mesenchymal stem cells prevent ost
Background: Local ischemia is the main pathological performance in osteonecrosis of the femoral head (ONFH).There is cur......
Exosomes released from human iPS-derived MSCs promote bone repair and regeneration by activating PI3
PURPOSE: The induced pluripotent stem cells-derived mesenchymal stem cells(iPS-MSCs)have emerged as a promising therapeu......
目的 Exosomes are vesicles of endocytic original released by many cells.The mechanism of exosome released is very compli......
Exosomal long RNA sequencing reveals abundant mRNA,circRNA and lncRNA in human blood as potential bi
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Exosomes derived from human endothelial progenitor cells accelerate cutaneous wound healing by promo
Chronic skin wounds represent one of the most common and disabling complications of diabetes. Endothelial progenitor cel......
