Cardiotoxicity相关论文
Objective:This study was designed to investigate the protective effects of didymin(Did)on doxorubicin(DOX)-induced cardi......
Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced car
Objective: To compare the cardioprotective efficacy of equimolar doses (50 mM/kg, p.o.) of phloretin and genistein again......
Rapid development of anticancer treatments in recent years has gready improved prognosis of cancer patients.However,with......
IGF1-PI3K-induced physiological cardiac hypertrophy:Implications for new heart failure therapies,bio
Heart failure represents the end point of a variety of cardiovascular diseases.It is a growing health burden and a leadi......
Bufalin is one of the main pharmacological and toxicological components of Venenum Bufonis and many traditional Chinese ......
Doxorubicin-loaded polymeric micelles based on bioactive polypeptides: Suppress invasion of melanoma
Few studies concerning the conformational effect of polypeptides on drug delivery have been reported,although conformati......
Early Changes of Right Ventricular Function and Morphology in Patients with Lymphoma Treated with An
Objective Although left ventricular dysfunction and abnormalities have been widelyrecognized in patients treated with an......
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Cardioprotective effects and treatment duration of beta-blockers in anthracycline-treated patients:a
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Cardiac safety of the adjuvant Trastuzumab in Chong Qing population:monocentric study of about 267 H
Objective Background and Objective: Trastuzumab adjuvant therapy remarkable improves the prognosis of breast cancer pati......
Objective Doxorubicin(DOX)is a chemotherapy medication used to treat various cancers.However,cardiotoxic side effects li......
Protection by pitavastatin from doxorubicin-induced acute cardiotoxicity through suppression of oxid
Aim: Doxorubicin (DOX) is an effective chemotherapeutic drug.However, its clinical application may be hampered by dose-d......
Objective: In this study,wemeasured the expression levelsof Top2B,which encodes topoisomerase Ⅱ β,in children with acu......
Tert-Butylhydroquinone ameliorates doxorubicin-induced cardiotoxicity by activating Nrf2 and inducin
Oxidative stress plays an important role in doxorubicin (DOX) induced cardiotoxicity.Nuclear factor E2-related factor-2 ......
Sunitinib,which is a multitargeted tyrosine-kinase inhibitor,exhibits antiangiogenic and antitumor activity.and extends ......
Metallothionein protects against doxorubicin-induced cardiac toxicity via regulation of mitochondria
OBJECTIVE Metallothionein (MT) has been previously shown to protect against doxorubicin (DOX)-induced cardiotoxicity, bu......
Protective effect of natural products against doxorubicin-induced cardiotoxicity:A systematic review
Background: Doxorubicin(Dox),an anthracycline antibiotic,is one of the most potent and widely used chemotherapeutic agen......
Objective: Doxorubicin is a widely used antineoplastic agent in clinics for treating a wide range of cancers.However,the......
目的：探讨检测血清心肌肌钙蛋白T (cTnT)和超声心动图参数在蒽环类药物早期心脏毒性评价中的临床意义。方法：检测使用蒽环类药物化疗......
Aconitine is a major bioactive diterpenoid alkaloid with high content derived from herbal aconitum plants.Emerging evide......
Interactions between bufadienolides derived from toad venom and verapamil in langendorff-perfused gu
Modulation of P-gp transport may lead to increased drug accumulation in normal tissues including heart with resulting in......
Exposure to water-accommodated fractions of two different crude oils alters morphology,cardiac funct
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目的:探索n 18F-脱氧葡萄糖(FDG)PET/CT显像早期诊断淋巴瘤治疗相关心脏毒性(TACT)的价值及分析不同评估标准的诊断效能。n ......
Chronic use of antipsychotic medications entails a dilemma between the benefit of alleviating psychotic symptoms and the......
Cardiotoxicity among Children Accidentally Exposed to Organophosphate Insecticides Coupled with Scor
Insecticides are toxic chemicals used at homes for controlling insects of public health importance and controlling agric......
Proteasome inhibitorlmatinib combinations exerts potentiated antileukemia efficacy but not cardiotox
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Doxorubicin is a highly effective anthracycline chemotherapy drug,but its dose-dependent cardiotoxicity limits its clini......
蒽环类药物作为细胞周期非特异性细胞毒性药物，是治疗儿童白血病最有效的药物，但其对心脏有严重的不良反应，影响患儿以后的生活质量及......
肿瘤已成为公共健康问题，抗肿瘤药物导致的心脏毒性极大地影响了患者的生存期及生活质量。超声心动图的经济、无创、普及性高等特点......
目的:研究枸杞多糖对多柔比星在比格犬中的药代动力学性质的影响.方法:8只比格犬连续12 d给予枸杞多糖胶囊(20mg/kg)或空胶囊,在第......
5-Fluorouracil (5-FU) is the most frequently used chemotherapy agent concomitant with radiotherapy in the management of ......
Evaluation of Epirubicin-induced Cardiotoxicity by Two-dimensional Strain Echocardiography in Breast
city on the systolic function of left ventricular subendocardial myocardium, and early monitor the epirubicin-induced ca......
As an effective anticancer drug,the clinical limitation of doxorubicin(Dox)is the time-and dose-dependent cardiotoxicity......
Noncoding RNAs in doxorubicin-induced cardiotoxicity and their potential as biomarkers and therapeut
Anthracyclines,such as doxorubicin(DOX),are well known for their high efficacy in treating multiple cancers,but their cl......
目的:观察辅酶Q10乳剂对阿霉素致小鼠心肌损伤的保护作用,并初步探讨其可能机制.方法:每天分别给予小鼠辅酶Q10胶囊或辅酶Q10乳剂......
目的:比较持续静脉缓慢滴注和静脉推注蒽环类药物心脏毒性的发生风险。方法:系统检索Cochrane图书馆、Elsevier、PubMed、Embase、......
Doxorubicin is a highly effective anthracycline chemotherapy drug, but its dose-dependent cardiotoxicity limits its clin......
Network pharmacological study on the mechanism of shenfu decoction in the treatment of cardiotoxicit
Objective: Doxorubicin is an efficient anthracycline drug for the treatment of tumor, however, its cardiotoxicity restri......
Effect of traditional Chinese medicine on anthracycline-induced cardiotoxicity in animal models:A sy
Objective: To evaluate the effect of traditional Chinese medicine (TCM) on anthracycline-induced car-diotoxicity (AIC) i......
,MicroRNAs participate in the cardioprotective activity of dexrazoxane against doxorubicin-induced c
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Background Doxorubicin is a widely used drug in all kinds of chemotherapy, but its application is limited by its cardiac......
Aim: To investigate the effects of deferiprone on doxorubicin-induced cardiotoxicity and determine its protection on car......
,Chronic cardiotoxicity of doxorubicin involves activation of myocardial and circulating matrix meta
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化疗是常规肿瘤治疗手段。随着临床诊断水平的提高、手术方法和化疗方案的不断改进，肿瘤患者的生存率得到了明显提高。然而，许多化疗......
目的探讨18F－2－(5－氟－戊基)－2－甲基丙二酸(18F－ML－10)PET/CT早期监测阿霉素(DOX)诱导的心脏毒性的可行性。方法将47只BALB/c小鼠按随机数字......
