Bufalin相关论文
Bufalin,中文名字是蟾蜍灵,它是一种Na+,K+-ATPase抑制剂,通过抑制钠钾交换增加细胞内钠离子含量;可调节钠钙泵使细胞内钙离子增加......
Background::Previous studies have shown that bufalin exerts antitumor effects through various mechanisms. This study aim......
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Near-infrared light-controllable bufalin delivery from a black phosphorus-hybrid supramolecular hydr
Bufalin is efficacious in treating various tumors,however,the clinical application of which is restricted by the myocard......
Bufalin is one of the main pharmacological and toxicological components of Venenum Bufonis and many traditional Chinese ......
The anti-nociceptive effect of bufalin, an active ingredient from toad venom via modulating voltage-
OBJECTIVE Toad venom (Venenum Bufonis) isalways used for analgesia in China from ancient to modern times, but the effect......
Restrain Effect of Three Anti-tumor Monomers Extracted from Chinese Medicine on The Growth of ECV304
Objective: Melittin,norcantharidin and bufalin are three extracts from Chinese herbal medicine in clinical application w......
Inhibitory effects of bufalin,an analgesic ingredient from toad venom on voltage-gated sodium channe
Bufonis Venenum(toad venom)is always used for analgesia in China from ancient to modern times.Bufalin,a non-peptide toxi......
Bufalin, a naturally occurring small-molecule compound from Traditional Chinese Medicine Chan su showed inhibitory effec......
Natural Product Bufalin Blocks Hepatocellular Carcinoma Proliferation and Migration by Targeting Mem
Bufalin,a main components of traditional chinese medicine from toad venom,is widely used to treat a variety of cancers i......
Objective:Bufalin is an effective drug for the treatment of liver cancer.But its high toxicity,poor water-solubility,fas......
Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines
<正> Aim:To investigate the antiproliferative activity and apoptosis-inducing effectsof bufalin on human osteosarcoma ce......
目的 :以低分化胃腺癌细胞系MGC 80 3为实验对象 ,观察了蟾酥提取物bufalin对其生长、分化的影响。方法 :应用台盼蓝染色法、 76 9......
Anti-tumor effect of bufalin on the orthotopic transplantation tumor model of human hepatocellular c
To investigate anti-tumor effect of bufalin on the orthotopic transplantation tumor model of humanhepatocellular carcino......
目的 探讨bufalin-mPEG-PLGA-PLL-cRGD体内药物靶向分布规律,为大肠癌的临床治疗提供实验依据和方法.方法 建立荷C26结肠癌裸鼠模......
Reversal effect of bufalin on multidrug resistance in K562/VCR vincristine-resistant leukemia cell l
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目的探讨bufalin通过细胞外信号调节激酶(ERK)/P90核糖体S6激酶2(RSK2)通路对裸鼠移植瘤增殖及凋亡的影响。方法建立裸鼠食管癌细......
目的：探讨蟾毒灵（Bufalin）对人脑胶质瘤 U251细胞生长增殖的影响。方法：采用四甲基偶氮蓝（MTT）比色法检测Bufalin 对人脑胶质瘤 U251细胞......
目的研究蟾毒灵对人结肠癌细胞株HCT116有氧糖酵解的影响。方法将人结肠癌细胞株HCT116分为蟾毒灵组和对照组,蟾毒灵组给予不同浓......
目的:观察蟾蜍灵对体外庆大霉素诱导的大鼠肾小管上皮细胞自噬的影响。方法:体外培养大鼠肾小管上皮细胞,分为正常对照组、庆大霉......
程序性细胞死亡又称凋亡,是一种由基因控制的细胞主动死亡过程,具有重要意义和复杂的分子机制.bcl-2基因家族是重要的凋亡调节基因......
,Bufalin induces apoptosis in human osteosarcoma U-20S and U-20S methotrexate3OO-resistant cell line
Aim: To investigate the antiproliferative activity and apoptosis-inducing effects of bufalin on human osteosarcoma cell ......
Aim: To investigate the inhibitory interactions of bufalin and CYP3A4.Methods: Recombinant human CYP3A4 was incubated wi......
,Bufalin derivative BF211 inhibits proteasome activity in human lung cancer cells in vitro by inhibi
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BF211,a bufalin (BF) derivative,exhibits stronger anti-cancer activity than BF but with potential cardiotoxicity.Fibrobl......
,Bufalin suppresses the migration and invasion of prostate cancer cells through HOTAIR, the sponge o
Bufalin,the major active component of the traditional Chinese medicine ChanSu obtained from the skin and parotid venom g......
Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantatio
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
OBJECTIVE To determine the characterization,anti-tumor efficacy and pharmacokinetics of bufalin-loaded PEGylated liposom......
目的研究蟾毒灵在胰腺癌CAPAN-2细胞系中的抗肿瘤作用,探讨其在胰腺癌中的抗肿瘤分子机制。方法 CCK-8法测定蟾毒灵对人胰腺癌CAPA......
目的探讨蟾蜍灵对体外醛固酮诱导的大鼠系膜细胞自噬的影响。方法体外培养大鼠系膜细胞,分为醛固酮组(A组)、蟾蜍灵组(B组)、醛固......
Toad venom, called as ChanSu in China, is a widely used traditional Chinese medicine (TCM) whose active components are m......
Anti-tumor effect of bufalin on the orthotopic transplantation tumor model of human hepatocellular c
To investigate anti-tumor effect of bufalin on the orthotopic transplantation tumor model of humanhepatocellular carcino......
目的 观察RGD修饰的载蟾毒灵多级靶向纳米粒对荷LM3肝癌裸鼠的靶向性,为蟾毒灵纳米粒的肝癌临床治疗提供依据和方法.方法 两组荷LM......
药效学实验结果表明，蟾酥镇冯的活性分主要存在于氯仿提取物中。分离蟾酥的氯仿提取物得到了脂蟾毒配基等６种单体化合物。６种单体化合......
目的:探讨蟾蜍灵对胃癌MGC-803细胞周期及周期蛋白的影响.方法:采用台盼蓝拒染法测定细胞增殖活力;瑞士-姬姆萨染色观察细胞形态学......
目的研究蟾蜍灵与全反式维甲酸（ATRA）联合对急性早幼粒细胞白血病（APL）细胞株NB4细胞的诱导分化作用。方法细胞存活率测定采用锥虫蓝拒......
目的：研究蟾毒灵对食管癌Kyse150细胞株放疗敏感性的影响。方法：使用CCK-8方法测定Kyse150细胞株中蟾毒灵的IC50值。通过克隆形成实......
目的:探讨蟾蜍灵对乳腺癌干细胞的增殖和侵袭能力的影响。方法:将人乳腺癌MDA-MB-231细胞系进行培养,采用流式细胞分选技术从中分......
目的:研究蟾蜍灵对白血病小鼠脾脏系数的影响,探讨其增强机体免疫功能的机制.方法:建立小鼠L7212白血病模型,以蟾蜍灵腹腔注射给药......
目的探讨细胞间隙连接通讯（GJIC）在蟾蜍灵抑制肾小球系膜细胞（MC）增殖中的作用及可能的机制。方法以体外培养的系膜细胞为研究对象,血......
<正> 六神丸具有清热、解毒、消炎、退肿等功效,蟾酥为六神丸的主药之一,其有效成分为一些骨架相同的甾体化合物,总称蟾毒内酯。含......
目的:探讨细胞外信号调解激酶(ERK)对蟾蜍灵诱导白血病细胞凋亡的影响.方法:形态学观察和流式细胞仪检测细胞凋亡.结果:0.5μmol/L......
目的研究蟾蜍灵对人急性淋巴白血病（CEM）细胞的作用。方法台盼蓝拒染法观察蟾蜍灵对细胞增殖的抑制作用;流式细胞术检测蟾蜍灵作用后......
目的：观察蟾蜍灵对HL-60细胞活力和凋亡的影响，对NF—κB通路的作用，探讨NF—KB通路在蟾蜍灵诱导HL-60细胞凋亡过程中的作用。方法：锥......
蟾毒灵属于传统中药蟾酥中的蟾酥二烯羟酸内脂之一,其结构与地高辛相似,是一种拓朴异构酶II抑制剂。它通过诱导细胞凋亡及阻滞细胞......
目的：探讨蟾蜍灵对人脑胶质瘤的作用。方法：将不同浓度的蟾蜍灵作用于胶质瘤细胞后，用CCK-8法检测细胞增殖抑制率，克隆形成实验检测细......
目的观察蟾毒灵对人胆管癌细胞QBC-939增殖和凋亡的影响，以及凋亡相关蛋白表达量的变化。方法体外培养人胆管癌QBC-939细胞，运用MTT......
Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantatio
瞄准：在裸体老鼠在人的肝细胞癌的 orthotopic 肿瘤模特儿调查反肿瘤活动和蟾蜍灵的调整 apoptosis 的机制。方法：人的肝细胞癌的 BE......
