CRYPTOTANSHINONE相关论文
Inhibitory Effect of Cryptotanshinone on Angiogenesis and Wnt/β-Catenin Signaling Pathway in Human U
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Objective Salvia miltiorrhiza has the characteristics of activating blood circulation and removing blood stasis,regulati......
Paclitaxel and Cryptotanshinone Loaded Temporal-controlled Nanoparticles for Combinatorial Cancer Th
Combination therapy has emerged as a promising strategy for treating multidrug resistant (MDR) cancer.In the previous st......
Cryptotanshinone has an inhibitory effect on angiogenesis and Wnt/ β-catenin signaling pathway in hu
Objective To investigate the anti-angiogenic effect of cryptotanshinone (CPT) on human umbilical vein endothelial cells ......
Endotoxin-and D-galactosamine-induced fulminant hepatic failure improved by the administration of cr
AIM Cryptotanshinone (CTN), one of the major constituents of tanshinones, was investigated for hepatoprotective effects ......
Effects of the coexisted components of Salvia on intestinal absorption of cryptotanshinone by the ev
Objective Cryptotanshinone, derived from the roots of Salvia miltiorrhiza Bge and Salviaprzewalskii Maxim, is the major ......
Objective: Anti-angiogenesis has been proposed as an important strategy for angiogenesis-related diseases.Cryptotanshino......
Objective: To investigate whether cryptotanshinone (CPT) could inhibit VEGF-induced angiogenesis and the effect of CPT o......
Activation of AMPK-TSC axis is involved in cryptotanshinone inhibition of mTOR signaling in cancer c
Cryptotanshinone (CPT), a fat-soluble tanshinone from Salvia miltiorrhiza Bunge, has been demonstrated to inhibit mTOR p......
Cryptotanshinione inhibits β-amyloid aggregation and protects damage from β-amyloid in SH-SY5Y cells
The deposition of amyloid β-protein (Aβ) fibrils into plaques within the brain parenchyma and along cerebral blood ves......
The amyloid precursor protein (APP) is cleaved enzymatically by nonamyloidogenic and amyloidogenic pathways.α-Secretase......
Cryptotanshinone,an orally bioactive herbal compound from Danshen,attenuates atherosclerosis in Apol
BACKGROUND AND PURPOSE: Cryptotanshinone (CTS) is a major bioactive diterpenoid isolated from Danshen, an eminent medici......
Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and m
BACKGROUND Approximately 90%of new cases of noncardiac gastric cancer(GC)are related to Helicobacter pylori(H.pylori),an......
目的 用LC-MS/MS法测定人血浆中隐丹参酮及丹参酮ⅡA的浓度.方法 血浆样品经甲醇沉淀蛋白处理,色谱柱:Symmetry C18(150. 0 mm×4.......
目的建立HPLC法测定复方葛根片中隐丹参酮和丹参酮ⅡA含量方法,以便更好的控制复方葛根片质量。方法采用HPLC法,色谱柱:SHMADZU VP......
目的:通过多指标综合评分法优选小儿清肺止咳巴布膏醇提工艺,确定最佳工艺参数。方法:以处方工艺中麻黄碱、隐丹参酮的提取率及浸......
AIM: To investigate the skeletal effects of total tanshinone in ovariectomized rats by analyzing cancellous bone histomo......
,Charactering the metabolism of cryptotanshinone by human P450 enzymes and uridine diphosphate glucu
Cryptotanshinone (CT) is the main active component in the root of Salvia miltiorrhiza Bunge (SMB) that displays antibact......
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目的探讨丹参酮类化合物对白血病干细胞(LSCs)的促凋亡作用。方法将二氢丹参酮Ⅰ、丹参酮Ⅰ、隐丹参酮与丹参酮ⅡA等4种丹参酮类化......
Simultaneous Determination of Five Hydrophilic and Lipophilic Components from roots of Salvia miltio
Objective A reversed-phase HPLC method was established for the simultaneous determination of five hydrophilic and lipoph......
目的 通过地塞米松体外诱导卵巢器宫胰岛素抵抗,探讨隐丹参酮对糖代谢、激素以及卵巢信号分子的影响.方法 40只18 g清洁级昆明白雌......
The reactions of cryptotanshinone and tanshinone ⅡA with cadaverine and putrescine were investigated. Six new compounds......
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目的探究隐丹参酮对大鼠吗啡条件性位置偏爱(CPP)效应形成的影响及其抗吗啡CPP的可能作用部位和机制。方法建立吗啡CPP效应模型观......
目的制备隐丹参酮纳米混悬剂,并评价其抗肿瘤活性。方法高压均质法制备纳米混悬剂后,测定其平均粒径、Zeta电位、形态、稳定性、体......
目的研究丹参中脂溶性成分隐丹参酮对Chang肝脏细胞细胞色素P450酶（CYP450）CYP3A4、CYP2C9表达的影响,明确丹参主要成分对CYP450酶的......
采用电喷雾电离质谱（ESI—MS）和电子轰击质谱（EI—MS）两种质谱技术，对隐丹参酮的结构和裂解途径分别进行了研究。采用EI—MS获得m／z296[M......
目的评价隐丹参酮对鸡胚尿囊膜(CAM)新生血管生成的抑制作用。方法在六日龄CAM上植入含隐丹参酮的甲基纤维素膜片并孵化48 h。解剖......
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目的研究隐丹参酮在Caco-2细胞模型中的吸收机制。方法用Caco-2细胞单层模型研究隐丹参酮的双向转运,并考察时间、药物浓度及抑制......
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目的研究隐丹参酮在大鼠小肠的吸收机制.方法用大鼠在体一过式肠灌流方法,通过肠系膜静脉插管采集血样,同时收集灌流流出液,以高效......
通过噬菌体十二肽库，以隐丹参酮为靶分子，筛选与隐丹参酮具有高亲和性的结合短肽。经过噬菌体十二肽库的3轮淘选，获得阳性噬菌体克隆，......
采用循环伏安法研究隐丹参酮在电极上的电化学行为及建立差示脉冲伏安对其测定的新方法。在pH4．0乙酸盐缓冲液中，氧化峰电流与隐丹参......
目的 研究隐丹参酮（Cryptotanshinone）的抗肿瘤活性及其抗血管生成的活性机制,为隐丹参酮治疗肿瘤提供数据支持。方法 培养结肠癌细......
目的建立丹参酮胶囊中隐丹参酮的含量测定法。方法采用HPLC法测定含量:ThermoODS(4.6mm×250mm,5μm)色谱柱,甲醇-水(75:25)为......
目的：建立一种快速准确同时测定丹参片中脂溶性及水溶性有效成分的方法。方法：建立PR-HPLC法，以甲醇-0．5％甲酸水溶液为流动相进行梯度洗......
利用循环伏安法（CV）、线性扫描伏安（LSV）、方波伏安法（OSWV）等电化学技术研究了隐丹参酮在玻碳电极（GCE）上的电化学氧化过程，并用计时电量法......
目的建立了同时测定大鼠血浆中4种丹参酮浓度的反相高效液相色谱方法，并将其应用于丹参醇提物中4种丹参酮的药动学研究。方法采用VP......
研究：研究隐丹参数（ＣＴ）及其代谢物丹参酮ＩＩＡ（ＴＳ）在猪体内的药代动力学。方法：实验猪５头，单剂量（１０ｍｇ·ｋｇ＾－１）ｉｖ隐丹参酮后，采用反相ＨＰＬＣ法检测ＫＣＴ及ＴＳ的血浆浓度。以二......
[目的]用HPLC测定丹参保健茶中隐丹参酮、丹参酮Ⅰ和丹参酮ⅡA的含量。[方法]色谱条件为：色谱柱为Insertsil ODS-SP（4.6mm×250 ......
目的: 体外培养猴骨髓间质干细胞(MSCs)并定向诱导分化为神经元样细胞. 方法: 体外分离培养猴MSCs,流式细胞仪检测其表面标志,用含......
目的 测定保心宁软胶囊中丹参素含量。方法 用高效液相色谱（HPLC）法测定保心宁软胶囊中丹参素含量，0DS-C18（150mm×6mm，5μm）色谱柱，......
目的：建立同时测定含丹参的中药制剂中隐丹参酮、丹参酮Ⅰ、丹参酮Ⅱ。含量的RP-HPLC法。方法：采用Microsorb—MV C18色谱柱（150mm......
目的探讨隐丹参酮对U937细胞的生长抑制作用及其作用机制。方法以不同浓度的隐丹参酮作用于体外培养的U937细胞,MTT法检测细胞生长......
在模拟生理条件下,研究了隐丹参酮与人血清白蛋白（HSA）的相互作用。荧光光谱分析结果说明,隐丹参酮对HSA的荧光猝灭过程为静态猝灭,......
目的：研究隐丹参酮对Akt活性的影响及其在抑制HepG2细胞生长中的作用。方法：Western印迹检测隐丹参酮对Akt磷酸化的影响;CCK-8法检测......
目的探讨隐丹参酮(CPT)对人肺腺癌细胞株A549和PC-9诱导凋亡的作用及其可能机制。方法不同浓度的CPT分别作用A549和PC-9细胞24和48......
目的：测定益肝颗粒中隐丹参酮和丹参酮ⅡA的含量。方法：采用Hanbon Lichrospher C18色谱柱；以甲醇-水（75：25）为流动相；流速1．0mL·min^......
目的：建立测定不同产地丹参中隐丹参酮、丹参酮Ⅰ、丹参酮ⅡA含量的方法。方法：采用反相高效液相色谱法。色谱柱为KromasilTMC18（250m......
目的建立克痤隐酮乳膏中隐丹参酮的含量测定方法。方法高效液相色谱法，迪马C18（250mm×4．6mm，5．0μm）色谱柱，甲醇-水（150：55）为流动相，检......
