Alzheimer\'s disease, the most common type of dementia among older adults, currently cannot be prevented or effectivel......

The repair of injured tissue is a highly complex process that involves cell proliferation, differentiation, and migratio......

Regular exercise has been shown to reduce the risk of Alzheimer\'s disease (AD).Our previous study showed that the pro......

Inflammatory responses,including glial cell activation and peripheral immune cell infiltration,are involved in the patho......

Astrocytes protect neurons by modulating neuronal function and survival.Astrocytes support neurons in several ways.They ......

Astrocytes are an abundant subgroup of cells in the central nervous system(CNS)that play a critical role in controlling ......

Prion diseases are infectious protein misfolding disorders of the central nervous system that result from misfolding of ......

After spinal cord injury (SCI), astrocytes gradually migrate to and surround the lesion, depositing chondroitin sulfate ......

Evidence suggests that rapid changes to supporting glia may predispose individuals with spinal cord injury (SCI) to such......

The mouse model of multiple cerebral infarctions, established by injecting fluorescent microspheres into the common caro......

Astrocytes are integral components of the central nervous system, where they are involved in numerous functions critical......

Electroacupuncture (EA) has been shown to reduce blood lipid level and improve cerebral ischemia in rats with hyperlipem......

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Chronic pain and itch are a pathological operation of the somatosensory system at the levels of primary sensory neurons,......

Previous genetic fate-mapping studies have indicated that embryonic glial fibrillary acidic proteinpositive (GFAP+) cell......

Increasing evidence suggests that spinal microglia regulate pathological pain in males.In this study,we investigated the......

Astrocytes are the most abundant cell type in the central nervous system (CNS).They provide trophic support for neurons,......

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Background High-grade(HG)gliomas are the most common primary brain tumors.Their malignancy is promoted by the complex cr......

In this study,we exposed adult aged rats to a chronic variable stress model and compare astroglial changes as a function......

Background: Multiple sclerosis (MS) is an autoimmune disease in the central nervous system (CNS) leading to demyelinatio......

α-Synuclein(α-Syn)is the most abundant protein found in Lewy bodies,a hallmark of Parkinsons disease(PD).Pathological ......

Aim: Metallothioneins are ubiquitous low molecular weight, cysteine-rich and metal binding proteins in mammals.The major......

In the milk-ejection reflex during lactation,activation of hypothalamic neurosecretory oxytocin neurons in the supraopti......

Aim: Protocatechuic acid (PCA), a phenolic compound, has been reported to exert neuroprotective effects, but its effect ......

Injection of complete Freunds adjuvant (CFA) to the hind paw of the rat is a widely used animal model of chronic inflamm......

Neurovascular unit mainly includes neuron,astrocytes and vascular endothelial cells.Brain functional repair after injury......

Global brain state dynamics regulate plasticity in local cortical circuits but the underlying cellular and molecular mec......

Although rare,infections of central nervous systems(CNS)often have devastating consequences.The mortality and morbidity ......

Aim: Microgtia and astrocytes in the brain play an important role in the development and/or progression of Alzheimers di......

Objective The 14-3-3 family, a group ofmultifunctional acidic proteins, exists predominantly in the brain.Up-regulation ......

Calcium binding proteins are well known to be expressed by different groups of hippocampal interneurons; however,whether......

The glutamate transporter-1 (GLT-1) exclusively expressed on the astrocytes which functions as a glutamate scavenger pro......

Neuropathic pain is one of the most widespread and intractable of human complaints.Neuroinflammation is recognized to pl......

DREAM (downstream regulatory element antagonist modulator),was involve in pain modulation.Its roles in astrocyte remains......

Objective To investigate the changes of expression of the anti-apoptotic protein Bcl-2 in neurons and activation of brai......

Parkinsons disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc......

The aim of our study is to investigate the changes in hippocampal synapses and their relation with learning-memory abili......

Whether astrocytes could express N-methyl-D-aspartate receptor (NMDA-R) is still controversial.We used primary culture o......

To investigate the damaging effect of hyperhomocysterinemia (HHcy) on cerebral cortex and hippocampus in apolipo-protein......

Disorders of copper metabolism are associated with neurological dysfunction including Wilsons disease (WD).WD is a autos......

Mitogen-activated protein kinases (MAPK)-mediated chemokine-cytokine networks in glial cells are likely involved in the ......

OBJECTIVE Ischemic stroke is currently treated with thrombolytic therapy with a drawback to induce hemorrhagic transform......

Objective: Caveolin-1 (Cav-1) is the main structural protein of caveolae, the micro-invaginations of the plasma membrane......

The aim of this article is to examine the toxic effects of hexabromocyclododecanes(HBCDs) on astrocytes primary culture ......

目的 研究新生大鼠星形胶质细胞(AC) β1整合素在缺氧缺血损伤及FDP干预处理后的表达变化,探讨β1整合素在星形胶质细胞缺氧缺血损......

Cationic liposome-mediated siRNA transfection is a common,easy,and economic gene silencing method.But this technique exh......

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