血液病常伴有染色体异常。作者报告一例骨髓纤维化伴有第8号染色体单体。该患1971年生,男性,胎龄9个月时受过X线照射,78年发病,发烧、淋巴结肿大、鼻出血。淋巴结活体组织检查为亚急性淋巴腺炎。但因贫血、血小板减少、白细胞增多和出现幼稚细胞而疑为恶性疾患。入院检查肝大1.5横指,全身淋巴结肿大,骨髓像检查细胞 Hematopathy often accompanied by chromosomal abnormalities. The authors report a case of myelofibrosis with chromosome 8 monomer. The suffering from 1971, male, 9 months gestational age by X-ray irradiation, 78 years of onset, fever, swollen lymph nodes, epistaxis. Lymph node biopsy is subacute lymphadenitis. However, due to anemia, thrombocytopenia, leukocytosis and naive cells and suspected malignant disease. 1.5 liver biopsy was admitted to the hospital, systemic lymphadenopathy, bone marrow cells like examination