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滴鼻药一般用于局部治疗,但近年来推荐将药物(如心得安)漓鼻吸收进入血循发挥全身作用。药物及附加剂用于鼻粘膜可损害鼻纤毛的运动,造成鼻粘膜纤毛清除率下降。作者发展了一种光电记录装置,可在体外记录鸡胚气管和人腺体的纤毛组织内纤毛的搏动频率。鼻充血治疗剂在20分钟内不会造成纤毛搏动频率减少50%,且作用可逆。很多抗生素对纤毛运动影响有限,作用可逆,只有杆菌肽(不可逆)和氯霉素(可逆)使纤毛运动停止1小时;皮质激素和色甘
Nasal drops are generally used for local treatment, but in recent years it is recommended that the drugs (such as propranolol) be absorbed into the bloodstream to play a systemic role. Drugs and additives for the nasal mucosa can impair the movement of the nasal cilia, resulting in decreased nasal mucociliary clearance rate. The authors developed a photoelectric recording device that records in vitro the pulsation frequency of cilia in the chicken trachea and human glandular cilia. Nasal congestion treatment does not result in a 50% reduction in ciliary beat frequency within 20 minutes and is reversible. Many antibiotics have a limited effect on ciliary motility and have a reversible effect, with only bacitracin (irreversible) and chloramphenicol (reversible) stopping ciliary movement for 1 hour; corticosteroids and ganache