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经胃镜活检的118例胃粘膜标本，HE染色，采用多媒体病理彩色图文分析系统，对细胞浆面积、细胞核面积、核浆比、核形状因子、N-异型指数进行均值、标准差、方差、标准误、最大值、最小值计算。结果慢性萎缩性胃炎（CAG）单纯型、增生型和肠化型与CAG的异型性型中，测得的五项指标差异均有显著性（P＜0．01）。CAG的异型性型与腺癌之间差异均无显著性（P＞0．05），细胞图像计算机分析为CAG的病理组织学分型，胃癌前病变的诊断提供了量化值。提示CAG的单纯型、增生型为良性病变，肠化型伴有灶性异型或发展为CAG的异型性型，CAG的异型性型是重要的癌前病变。
118 cases of gastric mucosa biopsied by gastroscope were stained with hematoxylin and eosin (HE), and the mean value, standard deviation, variance of the nuclear shape factor, nuclear shape factor, N-shaped index of cytoplasm area, Standard error, maximum, minimum calculation. Results There were significant differences in the five indicators measured in CAG atypia of CAG (P <0.01). There was no significant difference between atypical type and adenocarcinoma of CAG (P> 0.05). The computer image analysis of the cell images provided a quantitative value for the histopathological classification of CAG and the diagnosis of gastric precancerous lesions. Tip CAG simple type, hyperplastic benign lesions, intestinal metaplasia associated with focal or atypical CAG development, CAG atypia is an important precancerous lesions.