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本文介绍了检测慢性萎缩性胃炎壁细胞抗体的间接免疫荧光法。应用本法检测经纤维胃镜确诊的23例慢性萎缩性胃炎,同时以30名献血员的血清作为正常对照,检测结果,两者血清壁细胞抗体的阳性率有明显差异。据此,作者认为进一步研究萎缩性胃炎的有关免疫学发病机理,对于防治本病具有重要的意义。
This article describes the indirect immunofluorescence method for detecting antibodies to chronic atrophic gastritis parietal cells. The method was applied to detect 23 cases of chronic atrophic gastritis confirmed by fiberoptic gastroscopy, and the serum of 30 blood donors was used as a normal control. The results showed that there was a significant difference in the positive rate of serum wall cell antibodies between the two groups. Based on this, the author believes that further research on the pathogenesis of atrophic gastritis related to immunology has important implications for the prevention and treatment of this disease.