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目的探讨经尿道前列腺电切术(TURP)标本的部分或全部取材对前列腺癌漏诊的意义。方法对2008～2009年133例经病理诊断前列腺增生(BPH)的TURP标本全部取材进行病理检查,并与常规部分取材标本切片病理诊断的对比,必要时做免疫组化明确,观察诊断的一致性,有无漏诊前列腺癌。结果 133例BPH中发现漏诊前列腺癌(PCa)2例,前列腺上皮内瘤(PIN)13例,前列腺不典型性腺瘤样增生(AAH)9例,硬化性腺病(SM)4例,腺泡萎缩(PAH)3例。可疑标本均经免疫组化证实。结论 TURP标本部分取材和全部取材对前列腺癌的诊断有影响。
Objective To investigate the significance of partial or total extraction of transurethral resection of prostate (TURP) specimens for missed diagnosis of prostate cancer. Methods TURP specimens of 133 BPH patients diagnosed by pathology from 2008 to 2009 were collected for pathological examination. The pathological results were compared with the histopathological diagnosis of some partially taken specimens. Immunohistochemistry was used to confirm the consistency of diagnosis , With or without diagnosis of prostate cancer. Results There were 2 cases of PCa, 13 cases of prostate intraepithelial neoplasia (PIN), 9 cases of atypical adenomatous hyperplasia (AAH), 4 cases of sclerosing adenosis (SM), acinar atrophy (PAH) in 3 cases. Suspected specimens were confirmed by immunohistochemistry. Conclusion TURP specimens drawn and all of the material on the diagnosis of prostate cancer have an impact.