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评价泪然 (TearNatuarleⅡTN Ⅱ )和潇莱威 (Celluvisc)滴眼液在LASIK术后泪膜恢复中的作用。方法 :采用前瞻性研究 ,观察行LASIK治疗的 36 3只眼 ,根据术后用药不同随机分为三组 :对照组 ( 14 8眼 )、泪然组 ( 78眼 )、潇莱威组 ( 137眼 )。观察指标包括术前、术后一日、一周、一月的干眼症状、荧光素 (F1)和虎红 (Rb)染色、BUT、Schirmer′sⅠ试验。比较三组间有无统计学差异。结果 :术后一周时 ,TN Ⅱ组与Celluvisc组干涩症状均较对照组轻 (P <0 0 5 ) ,余时间点三组间无显著差异 (P >0 0 5 ) ;异物感各时间点三组间均无显著差异 (P >0 0 5 ) ;术后一日 ,TN Ⅱ组、Celluvisc组烧灼感与对照组有显著差异 (P <0 0 5 ) ;术后一周 ,TN Ⅱ组烧灼症状较对照组明显轻 (P <0 0 5 ) ,与Celluvisc组无差异。余时间点三组间无显著差异 (P >0 0 5 ) ;各时间点三组间Rb染色均无显著差异 (P >0 0 5 ) ;术后一月时 ,TN Ⅱ组角膜F1点状染色较对照组明显减少 (P <0 0 5 )。余时间点三组间无显著差异 (P >0 0 5 ) ;术后一周、一月时 ,三组BUT均较术前降低 (P <0 0 5 ) ,术后一月时 ,Celluvisc组BUT时间较对照组长 ,差异有显著性(P <0 0 5 ) ;术后一周时 ,TN Ⅱ组Schirmer′sⅠ试验结果较对照组高 ,与Celluvi
To evaluate the effect of TearNatuarleⅡTN Ⅱ and Celluvisc eye drops on tear film recovery after LASIK. Methods: A prospective study was conducted to observe 363 eyes treated with LASIK. The patients were randomly divided into three groups according to their postoperative medication: control group (14.8 eyes), soreness group (78 eyes), Xiaolaisiwei group (137 eyes) eye). Observations included preoperative, postoperative day, week, and January dry eye symptoms, fluorescein (F1) and tiger red (Rb) staining, BUT, Schirmer’s test. Compare the three groups with or without statistical difference. Results: After one week, the symptoms of dryness in TN Ⅱ group and Celluvisc group were lighter than those in control group (P <0.05), and there was no significant difference among the three groups after one week (P> 0.05) There was no significant difference between the three groups (P> 0.05). On the first day after operation, the burning sensation in TN Ⅱ group and Celluvisc group was significantly different from that in control group (P <0.05); one week after operation, TN Ⅱ group cauterized The symptoms were significantly lower than those in the control group (P <0.05), but no difference with the Celluvisc group. There were no significant differences among the three groups at any time point (P> 0.05). There was no significant difference in Rb staining between the three groups at each time point (P> 0.05) Compared with the control group, staining decreased significantly (P <0 05). There was no significant difference between the three groups at any time point (P> 0.05). One week after operation and one month after operation, the BUT in all three groups decreased compared with that before operation (P <0.05) The time was longer than the control group, the difference was significant (P <0 05); one week after surgery, TN Ⅱ group Schirmer’s Ⅰ test results compared with the control group, and Celluvi