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目的探讨合理运用降压药物对高血压病合并急性脑梗死患者血压控制和肢体功能康复的影响。方法将本院收治的84例高血压病合并急性脑梗死患者按照患者(或家属)意愿,分为观察组和对照组各42例;对照组采用常规脑梗死治疗措施;观察组在常规治疗的同时,合理运用降压药物,连续使用8周,并随访1年;比较2组治疗前后的血压控制情况、肢体功能评分(FMA评分和Barthel评分),记录2组病情加重率和复发率。结果观察组血压控制率显著高于对照组(P<0.05);治疗第12、24、48周后观察组FMA和Barthel评分均显著高于对照组(P<0.05);观察组1年内病情加重率和复发率均显著低于对照组(P<0.05)。结论高血压病合并脑梗死患者合理运用降压药物能够显著控制血压,改善肢体功能,降低复发率和加重率。
Objective To investigate the effect of rational use of antihypertensive drugs on blood pressure control and rehabilitation of patients with essential hypertension complicated with acute cerebral infarction. Methods Eighty-four patients with hypertension complicated by acute cerebral infarction admitted to our hospital were divided into observation group and control group according to the wishes of the patients (or their families), 42 cases in each group. The control group was treated by conventional cerebral infarction. At the same time, the rational use of antihypertensive drugs, continuous use of 8 weeks, followed up for 1 year; compared two groups before and after treatment of blood pressure control, limb function score (FMA score and Barthel score), recorded two groups of exacerbations and relapse rates. Results The blood pressure control rate in the observation group was significantly higher than that in the control group (P <0.05). The FMA and Barthel scores of the observation group were significantly higher than those of the control group (P <0.05) after 12, 24 and 48 weeks of treatment. Rate and recurrence rate were significantly lower than the control group (P <0.05). Conclusion The rational use of antihypertensive drugs in hypertensive patients with cerebral infarction can significantly control blood pressure, improve limb function, reduce the recurrence rate and aggravating rate.