To determine patients’quality of life (QOL) after macular translocation with 360°peripheral retinectomy (MT360) for age-related macular degeneration. Prosp ective, interventional, consecutive, noncomparative case series. A prospective s tudy assessed QOL 1 year after MT360 and its relation to postoperative visual fu nction. The 25-item National Eye Institute Visual Function Questionnaire (NEIVF Q-25) and the Medical Outcomes Study 12-item short form (SF-12) health survey were used to assess vision-related QOL and general health, respectively. Surve ys were administered preoperatively and postoperatively. Postoperative NEIVFQ-2 5 QOL and SF-12 subscale scores for all patients were compared with the preoper ative scores. Preoperative and postoperative distance and near visual acuities ( VAs) and reading speed were assessed. Changes in NEIVFQ-25 QOL subscale scores were compared in patients with and without improved visual function. Postoperati ve NEI VFQ-25 QOL subscale scores in patients with distance VA of ≥69 Early Tr eatment Diabetic Retinopathy Study letters, near VA of ≥20/70, and reading spee d of ≥90 words per minute were compared with subscale scores in patients with w orse postoperative visual function. National Eye Institute VFQ-25 and SF-12 QO L scores and their association with distance VA, near VA, and reading speed. In total, 50 patients with a mean age of 76.9 years were studied. Postoperative mea n NEIVFQ25 QOL scores were higher than the preoperative mean scores, and this di fference was significant for important vision-specific subscales. Patients with improved visual function had greater mean changes in NEIVFQ-25 QOL scores than those with no improvement. Patients with the outlined higher levels of visual f unction had greater mean NEIVFQ-25 QOL scores than those who had worse visual f unction. Preoperative and postoperative mean SF-12 QOL scores were similar. Mac ular translocation with 360°peripheral retinectomy was associated with improvem ent in vision-related QOL. The amount of improvement was greatest in patients w ith postoperative improvement in visual function, and the best postoperative vis ion-related QOL was seen in patients with better postoperative visual function. This was not associated with a change in patients’general health. To determine patients’ quality of life (QOL) after macular translocation with 360 ° peripheral retinectomy (MT360) for age-related macular degeneration. Prosp ective, interventional, consecutive, noncomparative case series. A prospective s tudy assessed QOL 1 year after MT360 and The relation to postoperative visual fuction. The 25-item National Eye Institute Visual Function Questionnaire (NEIVF Q-25) and the Medical Outcomes Study 12-item short form (SF-12) health survey were used to assess vision-related QOL and General health, respectively. Surve ys were administered preoperatively and postoperatively. Postoperative NEIVFQ-2 5 QOL and SF-12 subscale scores for all patients were compared with the preoper ative scores. Preoperative and postoperative distance and near visual acuities (VAs) and reading speed Changes in NEIVFQ-25 QOL subscale scores were compared in patients with and without improved visual function. Postoperati ve NEI VFQ-25 QOL subscale scores in pati ents with distance VA of ≥69 Early Tr eatment Diabetic Retinopathy Study letters, near VA of ≥20 / 70, and reading spee d of ≥90 words per minute were compared with subscale scores in patients with w orse postoperative visual function. National Eye Institute VFQ-25 and SF-12 QO L scores and their association with distance VA, near VA, and reading speed. In total, 50 patients with a mean age of 76.9 years were studied. Postoperative mea n NEIVFQ25 QOL scores were higher than the preoperative mean scores, and this di fference was significant for important vision-specific subscales. Patients with improved visual function had greater mean changes in NEIVFQ-25 QOL scores than those with no improvement. Patients with the outlined higher levels of visual f unction had greater mean NEIVFQ-25 QOL scores than those who worse worse than visual unction. Preoperative and postoperative mean SF-12 QOL scores were similar. Mac ular translocation with 360 ° peripheral retinectomy was associated with impr ovem ent iThe amount of improvement was greatest in patients w ith postoperative improvement in visual function, and the best postoperative vis ion-related QOL was seen in patients with better postoperative visual function. This was not associated with a change in patients ’general health.