论文部分内容阅读
直肠癌患者术后夏发率及死亡率较高。术前对患者加以辅助治疗,如放疗、化疗,可在一定程度上降低复发率,并可在清除局部病灶的前提下,提高肛门括约肌的保留率。但不同患者对术前放化疗的敏感度不同。为了探讨究竟哪些患者可受益于术前放化疗,以期对不同敏感度的患者采取不同的治疗方案,本文以免疫组化染色方法检测p53蛋白产物,并与患者对放化疗的敏感度进行了相关性研究。 研究对象为1990年7月至1995年7月的42例重度直肠癌患者,男30例,女12例,平均年龄63岁。所
The postoperative summer rate and mortality were higher in patients with rectal cancer. Preoperative adjuvant treatment of patients, such as radiotherapy and chemotherapy, can reduce the recurrence rate to a certain extent, and can improve the retention rate of the anal sphincter under the premise of clearing local lesions. However, different patients have different sensitivities to preoperative chemoradiotherapy. In order to investigate which patients can benefit from preoperative chemoradiotherapy in order to adopt different treatment options for patients with different sensitivities, this study examined the production of p53 protein by immunohistochemical staining and correlated the patient’s sensitivity to radiochemotherapy. Sexual research. The subjects studied were 42 patients with severe rectal cancer from July 1990 to July 1995. There were 30 males and 12 females with an average age of 63 years. By