七个独立进行的随机对照试验表明,用普洛萘尔预防性治疗1～2年可使肝硬化静脉曲张首次出血的危险性降低。但许多肝硬化病人因药物禁忌和/或副作用而不适用普洛荼尔,另有约1/3病人用药后血液动力学反应不满意。二硝酸异山梨醇酯和5-单硝酸异山 Seven independent randomized controlled trials have shown that prophylactic treatment with pinafor 1 to 2 years can reduce the risk of first-time hemorrhagic cirrhosis of the varicocele. However, many patients with cirrhosis are not eligible for propofol due to drug contraindications and / or side effects, and about one-third of patients are dissatisfied with their hemodynamic response. Isosorbide dinitrate and Isomonasil 5-mononitrate