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本文以S180瘤细胞株为靶细胞建立了动物肿瘤模型，分别以TNF单用、TNF－CTX合用和脂质体－TNF复合物三种给药方式，进行了肿瘤坏死因子（TNF）体内抗癌试验。结果表明，TNF——CTX合用，具有协同抗瘤作用，且能减轻副作用；脂质体——TNF复合物能明显减轻TNF的毒性反应，而不影响TNF的抗癌作用。
An animal tumor model was established using the S180 tumor cell line as a target cell. Tumor necrosis factor (TNF) was used as an anti-cancer agent in vivo using TNF alone, TNF-CTX, and liposome-TNF complexes, respectively. test. The results showed that TNF-CTX combined with a synergistic anti-tumor effect, and can reduce the side effects; liposome - TNF complex can significantly reduce the toxicity of TNF, without affecting the anti-cancer effect of TNF.