1988年2月～1991年12月,402例育龄妇女服用国产复方左旋18甲基炔诺酮(LNG)三相片7030周期,仅1例因漏服5片药而怀孕,校正避孕有效率为100%。周期控制好,经期间出血和无撤退性出血发生率各为1.92%和0.05%。副反应发生率为周期总数的4.1%。药源性停药65例,占服药总人数的16.17%。服药6～59周期每100妇女药源性净累计终止率为0.1266～0.2090。定期复查肝、肾功能、尿糖、血压和体重等均未发现异常。对复方LNG三相片的避孕效果、机理、周期控制及其优越性进行讨论。 From February 1988 to December 1991, 402 women of childbearing age took 7030 cycles of domestic compound levonorgestrel norepinephrine (LNG) in three phases, only 1 patient became pregnant due to missing 5 pills. The effective rate of contraceptive correction was 100 %. Cycle control is good, the bleeding during the period and the rate of non-withdrawal bleeding were 1.92% and 0.05%. The incidence of side effects was 4.1% of the total number of cycles. Drug-based withdrawal 65 cases, accounting for 16.17% of the total number of taking the drug. Medication 6 to 59 cycles per 100 women net source termination rate was 0.1266 ~ 0.2090. Regular review of liver and kidney function, urine sugar, blood pressure and weight were found no abnormalities. The contraindication effect, mechanism, period control and its superiority of compound LNG three-phase photos are discussed.