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目的实验观察地塞米松（ｄｅｘａｍｅｔｈａｓｏｎｅ，ＤＸＭ）注入家兔眼前房的不良反应。方法将３０只兔右眼前房注入ＤＸＭ０．２ｍｌ（含０．２ｍｇ），左眼前房注入ＢＳＳ液作对照，术后观察角膜及前房的反应。结果试验组的眼角膜及前房反应明显高于对照组。结论结合ＤＸＭ的药剂学资料，认为使用不纯的ＤＸＭ制剂作眼内注射是不安全的。
Objective To observe the adverse reactions of injecting dexamethasone (DXM) into the anterior chamber of rabbits. Methods Thirty rabbits were injected DXM 0.2ml (0.2mg) into the right anterior chamber and BSS solution into the left anterior chamber as control. The cornea and anterior chamber were observed after operation. Results The cornea and anterior chamber in the experimental group were significantly higher than those in the control group. Conclusions In combination with the pharmacy data from DXM, it is not safe to use impure DXM formulations for intraocular injection.