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目的制定梅毒螺旋体抗体(抗-TP)筛查反应性献血者归队策略。方法收集全国12家采供血机构2013年12月-2015年6月抗-TP ELISA筛查反应性献血者标本373例,经ELISA、TPPA确证检测或/和8周后追踪检测,鉴别这些献血者抗-TP是否为真(假)阳性,确定其是归队还是继续屏蔽。结果在373例抗-TP筛查反应性标本中,确证(经确证试验和/或追踪)抗-TP阳性145例(38.9%,145/373)、不确定4例,此149名献血者可作暂时性屏蔽;抗-TP阴性114例(30.6%,114/373),其献血者可以归队;110例(29.5%,110/373)因未成功追踪而被放弃。结论抗-TP筛查反应性献血者的归队策略:确证试验ELISA有反应性、TPPA为阳性者,判为抗-TP阳性,暂时性屏蔽;确证试验ELISA有(或无)反应性而TPPA是阴性,8周后追踪检测。
Objective To develop a strategy to screen for reemergent blood donors by Treponema pallidum antibody (anti-TP). Methods A total of 373 anti-TP ELISA screening reactive blood samples from 12 blood collection and supply institutions in China were collected from December 2013 to June 2015. The samples were confirmed by ELISA, TPPA confirmatory test and / or 8 weeks follow-up test to identify these blood donors Anti-TP is true (false) positive, to determine whether it is rejoin or continue to shield. Results Of 373 anti-TP screening reactivity samples, 145 (38.9%, 145/373) anti-TP positive were confirmed (confirmed and / or tracked) and 4 were uncertain. The 149 donors As a temporary shield; anti-TP negative in 114 cases (30.6%, 114/373), the donor can return to the team; 110 cases (29.5%, 110/373) were not tracked due to be abandoned. CONCLUSIONS: The strategy of reversion to anti-TP screening responders is to confirm that the test ELISA is reactive and that TPPA is positive, which is judged as anti-TP positive and temporarily shielded. It is confirmed that the test ELISA has (or no) reactivity and TPPA is Negative, follow-up test after 8 weeks.