VEGF-A及其不同异构体在肾脏疾病中的研究进展

来源 :生理学报 | 被引量 : 0次 | 上传用户：a9249228

【摘要】

：

血管内皮生长因子-A(vascular endothelial growth factor-A,VEGF-A)是重要的血管生成因子,肾脏足细胞与上皮细胞是分泌VEGF-A的主要细胞类型,在肾脏病理生理过程中发挥重要作用.近年来随着对VEGF-A不同异构体功能的深入研究,以及对细胞外囊泡(extracellular vesicles,EVs)作为VEGF-A的新型分泌方式的认识,进一步关注和深入研究VEGF-A在肾脏损伤中的作用具有重要意义.本文主要从VEGF-A的表达、分泌、调控和生物学功能及VEGF-A

【作者】

：

敬婧仲鑫刘必成吕林莉

【机构】

：

东南大学肾脏病研究所,东南大学附属中大医院肾脏科,南京210009

【出处】

：

生理学报

【发表日期】

：

2022年1期

【关键词】

：

血管内皮生长因子肾脏疾病内皮细胞细胞外囊泡外泌体

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VEGF-A及其不同异构体在肾脏疾病中的研究进展

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