论文部分内容阅读
目的查明深圳市首例输血性恶性疟病例的感染原因。方法查阅患者的病历档案,收集流行病学资料;镜检法和快速诊断试验(RDT)检测患者和献血员血样中疟原虫及其分泌的特异性抗原。结果患者发病10 d前因手术接受输血,临床症状主要为发热、咳嗽伴肌肉酸痛;血常规提示:红细胞计数、血小板计数及血红蛋白浓度下降;血涂片镜检查见恶性疟原虫小滋养体。患者为深圳本地居民,近1年无疟疾疫区外出史;提供血液的1名献血员曾在非洲喀麦隆疟疾流行区工作10个月,其献血留存血样RDT检测恶性疟原虫阳性。结论根据临床表现、疟原虫检查结果,结合流行病学分析判断为经输血传播的恶性疟个案。
Objective To identify the cause of infection in the first case of blood transfusion malaria in Shenzhen. Methods Patient records were collected and epidemiological data were collected. Microscopic examination and rapid diagnostic test (RDT) were used to detect blood plasma samples of patients and blood donors and their specific antigens. Results The patients were transfused by operation 10 days before the onset of symptoms. The main clinical symptoms were fever and cough with muscle soreness. The blood routine showed the decrease of erythrocyte count, platelet count and hemoglobin. The blood smear microscopy showed the small trophozoites of Plasmodium falciparum. The patient was a resident of Shenzhen for almost a year without any malaria-endemic area. A blood donor who had been working in a malaria-endemic area of Cameroon in Africa for 10 months had blood donation blood samples RDT for positive detection of Plasmodium falciparum. Conclusion According to the clinical manifestations, the test results of malaria parasites, combined with epidemiological analysis of transfusion-transmitted cases of falciparum malaria.