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根据基层医院特点,通过合理的药学干预,可以使不同种类抗生素的使用更趋合理。建立药学干预四项措施,1)对抗生素实行分级管理制度;2)逐月对各科室抗生素使用情况进行全院通报;3)启动抗生素预警制度;4)临床药师下临床加强与医师的交流沟通。对2007(干预前)、2008(干预后)两个年度呼吸内科抗生素使用情况进行对比分析。抗生素使用从集中于一类药品转向多种轮替使用,干预前与干预后抗生素的使用情况具有显著性差异(P<0.01)。合理的药学干预是抗生素合理使用的有效手段。
According to the characteristics of primary hospitals, the rational use of pharmaceutical interventions can make the use of different types of antibiotics more reasonable. The establishment of four measures of pharmaceutical intervention, 1) the implementation of hierarchical management of antibiotics; 2) month by month on the use of antibiotics in various sections of the hospital informed; 3) start the antibiotic warning system; 4) clinical pharmacists to strengthen clinical communication with the physician . A comparative analysis of the use of respiratory medical antibiotics between 2007 (pre-intervention) and 2008 (post-intervention) years was conducted. The use of antibiotics shifted from concentrating on a class of drugs to using multiple rotations. There was a significant difference in the use of antibiotics before and after intervention (P <0.01). Rational drug intervention is an effective means of rational use of antibiotics.