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目的观察羊膜制品在重度宫腔粘连中的临床治疗效果。方法选取重度宫腔粘连患者100例,根据治疗方案不同分为对照组和观察组各50例。对照组采用Foley球囊治疗,观察组采用羊膜制品治疗,比较两组治疗效果。结果两组手术前宫腔粘连评分及月经量评分差异无统计学意义(P>0.05);观察组手术后宫腔粘连评分显著低于对照组(P<0.05);观察组手术后月经量评分显著高于对照组(P<0.05);两组治疗前子宫内膜厚度差异无统计学意义(P>0.05);观察组术后3个月、术后6个月子宫内膜厚度显著大于对照组(P<0.05);观察组术后6个月宫腔再粘连发生率为18.00%,显著低于对照组的28.00%(P<0.05)。结论与Foley球囊治疗相比,重度宫腔粘连患者采用羊膜制品治疗效果更理想,能改善月经量,降低术后粘连评分,值得推广应用。
Objective To observe the clinical effect of amniotic membrane products in severe intrauterine adhesions. Methods 100 cases of severe intrauterine adhesions were selected, divided into control group and observation group of 50 cases according to the different treatment options. The control group was treated with Foley balloon and the observation group was treated with amniotic membrane products. The therapeutic effect was compared between the two groups. Results There was no significant difference in the intrauterine adhesion score and menstrual volume score between the two groups before operation (P> 0.05). The intrauterine adhesion score of the observation group was significantly lower than that of the control group (P <0.05) (P <0.05). There was no significant difference in the thickness of endometrium between the two groups before treatment (P> 0.05). The thickness of endometrium in the observation group at 3 months and 6 months after operation was significantly higher than that in the control group (P <0.05). The incidence of intrauterine adhesions in the observation group was 18.00% at 6 months after operation, which was significantly lower than that in the control group (28.00%, P <0.05). Conclusion Compared with Foley balloon therapy, amniotic membrane products in patients with severe intrauterine adhesions have better therapeutic effect, which can improve menstrual flow and reduce postoperative adhesion score, which is worth popularizing and applying.