在肝硬变的发病过程中,尤其在失代偿情况下,常伴有肾脏功能损害,表现为尿量显著减少、氮质血症,甚至迅速发展为肾功能衰竭、尿毒症。近年来,由于肝硬变合併症的治疗有所改进,对本综合征的研究亦日益深入。肝硬变合併肾功能损害大致有以下三类:①急性肾小管坏死:有明确的病因与临床表现,实验室检查发现尿中含蛋白质,管型、白细胞和红细胞较多,尿比重低,尿钠含量相对增高,而肌酐(尿/血浆) In the pathogenesis of cirrhosis, especially in the case of decompensation, often accompanied by renal dysfunction, showed a significant decrease in urine output, azotemia, and even rapid development of renal failure, uremia. In recent years, due to the improvement of the treatment of liver cirrhosis, the study of this syndrome is also increasingly in-depth. Cirrhosis complicated with renal damage generally have the following three categories: ① acute tubular necrosis: a clear etiology and clinical manifestations, laboratory tests found that urine contains more protein, tubular, white blood cells and red blood cells, urine specific gravity is low, urine Sodium content is relatively high, while creatinine (urine / plasma)