NDRG1基因是1种新近发现的与细胞分化相关的基因,本文就NDRG1与肿瘤的研究现状做一综述。1 NDRG1基因的分子生物学特征研究发现[1],NDRG1基因定位于人染色体8q24.3,长约60kb,包含16个外显子和15个内含子,其中含有1个与第1外显子和第1内含子5′端重叠的CpG岛,同时在第1外显子的 The NDRG1 gene is a newly discovered gene associated with cell differentiation. In this review, the current status of NDRG1 and tumor research is reviewed. 1 NDRG1 gene molecular characteristics of the study found that [1], NDRG1 gene located on the human chromosome 8q24.3, about 60kb, contains 16 exons and 15 introns, which contains a 1 and the first explicit The CpG islands overlapped with the first intron at the 5 ’end of the first intron and at exon 1