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目的探讨原发性胆汁反流性胃炎(BRG)青年患者体重减轻的相关因素。方法40例原发性BRG青年患者为观察组,20例青年志愿者为对照组,两组分别行胃镜检查、体重指数测定、24h胃内pH和胆汁反流监测。观察组还记录临床症状,然后分别行统计学处理。结果观察组体重指数为19.41±2.31,对照组为20.97±2.08,两组有显著性差异(P=0.01),其中观察组蛋白质-热量营养不良1级9例,2级5例,3级1例;对照组1级1例,无2、3级者。胃内胆红素abs>0.14的时间百分比与体重指数呈负相关(r=-0.304,P=0.018),与症状程度呈正相关(F=23.54,P=0.001)。结论原发性BRG可引起体重减轻,部分患者发生不同程度的蛋白质-热量营养不良,其机制可能与BRG引起的消化不良有关。
Objective To investigate the related factors of weight loss in young patients with primary bile reflux gastritis (BRG). Methods Forty young patients with primary BRG were selected as observation group and 20 young volunteers as control group. Gastroscopy, body mass index, 24h gastric pH and bile reflux were monitored in both groups. The observation group also recorded clinical symptoms, and then were statistically processed. Results The body mass index of the observation group was 19.41 ± 2.31 and that of the control group was 20.97 ± 2.08, with significant difference between the two groups (P = 0.01). The observation group included 9 cases of grade 1, 5 cases of grade 2, 3 cases of grade 1 Cases; control group 1 in 1 case, no 2,3 grade. The time percentage of gastric bilirubin> 0.14 was negatively correlated with body mass index (r = -0.304, P = 0.018), and positively correlated with the degree of symptoms (F = 23.54, P = 0.001). Conclusion Primary BRG can cause weight loss, and some patients have different degrees of protein - calorie malnutrition, the mechanism may be related to indigestion caused by BRG.