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目的：应用时间—密度曲线分析比较不同注射量和注速对肝增强峰值造成的影响，选择适合肝脏螺旋增强扫描的较佳注射方案。方法：４８例正常肝脏患者，随机分成四组，以不同注射量和注速，单时相注射离子型造影剂，于肝门区水平行单层动态扫描，分别求出肝实质、主动脉、脾脏增强峰值及其发生时间，并进行统计学处理。结果：１００ｍｌ注射量比８０ｍｌ注射量产生更高的肝增强峰值（Ｐ＜０．０５）；３ｍｌ／ｓ注速与２ｍｌ／ｓ注速产生相似的ＰＨＣＥ（Ｐ＞０．０５），但前者发生更大的造影剂毒副反应。结论：１００ｍｌ注射量、２ｍｌ／ｓ注速为最佳注射方案，适合肝脏螺旋增强扫描
OBJECTIVE: To compare the effect of different injection volume and injection speed on peak liver enhancement by time-density curve analysis, and select the best injection scheme for liver spiral enhancement scanning. Methods: Forty-eight patients with normal liver were randomly divided into four groups. The rats were injected with Ionic Contrast Agent at different injection rates and injection velocities, single-phase dynamic scanning at the level of the hepatic portal. The liver parenchyma, aorta, Splenomegaly peak and its occurrence time, and statistical analysis. Results: The 100 ml injection produced a higher peak of hepatic enhancement (P <0.05) than the injection of 80 ml (P <0.05). The injection rate of 3 ml / s and 2 ml / Larger contrast agent toxicity. Conclusion: 100ml injection volume, 2ml / s injection rate is the best injection scheme, suitable for hepatic spiral enhanced scan