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观察了α＿１型基因工程干扰素治疗尖锐湿疣分别用皮损内注射和肌肉注射治疗１７例和１３例的疗效对比，每次１００万ｕ，３周内共９次。皮损注射组痊愈４例（２３．６％），显效７例（４１．２％），有效和无效各３例（１７．６％）。肌肉注射组痊愈和显效各１例，有效３例，无效８例。结果显示前者疗效优于后者（Ｐ＜０．０１）。皮损注射组出现副作用７例（４１．２％），主要为乏力等流感样症状。
The therapeutic effects of α_1 genetically engineered interferon in the treatment of condyloma acuminatum were compared between 17 cases and 13 cases treated with intradermal injection and intramuscular injection respectively, 1 million u each and 9 times within 3 weeks. Lesions in the injection group were cured in 4 cases (23.6%), markedly effective in 7 cases (41.2%), effective and ineffective in 3 cases (17.6%). Intramuscular injection group cured and effective in 1 case, effective in 3 cases, 8 cases. The results show that the former is better than the latter (P <0.01). There were 7 cases (41.2%) of the side effects in the skin lesion injection group. The main symptoms were flu-like symptoms such as fatigue.