中耳渗液(下称MEE)系指鼓膜完整,早期无明显症状及急性炎症体征的一种中耳渗出性疾病。发病率逐年增高,目前已成为耳鼻喉科常见病和儿童致聋的主要原因。发病原因与机制至今不清,渗液以粘稠和顽固为特征,治疗较困难。现就MEE有关动物实验和临床研究某些进展介绍如下。 Middle ear exudate (hereinafter referred to as MEE) refers to a tympanic membrane integrity, no obvious early symptoms and signs of acute inflammation of the middle ear exudative disease. The incidence rate increases year by year, has now become the common cause of otolaryngology and deafness in children the main reason. The etiology and mechanism are still unclear, exudate is characterized by stickiness and stubbornness, the treatment is more difficult. Some of the developments in animal experiments and clinical studies on MEE are presented below.