论文部分内容阅读
目的:探讨米非司酮在库欣综合征患者中的疗效以及不良反应的发生情况,为临床用药提供依据。方法:对药师参与的1例库欣综合征患者采用米非司酮治疗的病例进行分析。结果:米非司酮可以显著改善患者的高皮质醇血症及并发症,但应注意患者低血糖的风险,及时停止胰岛素治疗。结论:米非司酮应用于库欣综合征患者可以显著降低血糖水平,改善库欣容貌,但同时需密切监测血钾水平,警惕低钾血症的发生。
Objective: To investigate the efficacy of mifepristone in patients with Cushing’s syndrome and the incidence of adverse reactions, provide the basis for clinical use. Methods: A case of Cushing’s syndrome treated by pharmacists was analyzed with mifepristone treatment. Results: Mifepristone can significantly improve the patients with hypercortisolemia and complications, but should pay attention to the risk of hypoglycemia in patients with timely cessation of insulin treatment. Conclusion: The use of mifepristone in patients with Cushing’s syndrome can significantly reduce blood glucose levels and improve Cushing’s appearance, but at the same time, it is necessary to closely monitor serum potassium levels and be alert to hypokalemia.