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目的探讨芪明颗粒治疗早期糖尿病肾病的临床效果。方法 76例早期糖尿病肾病患者,随机分为对照组和观察组,各38例。对照组采用常规治疗方法 ,观察组采用常规治疗联合芪明颗粒治疗。观察两组临床疗效。结果治疗后观察组水肿评分、24 h尿量、尿素氮(BUN)、肌酐(Cr)均优于对照组(P<0.05);治疗后观察组空腹血糖(FBG)为(9.1±1.3)mmol/L、低密度脂蛋白胆固醇(LDL-C)为(4.3±0.4)mmol/L、甘油三酯(TG)为(2.7±0.7)mmol/L、总胆固醇(TC)为(5.8±0.8)mmol/L,均分别优于对照组的(6.2±0.9)、(3.4±0.5)、(1.8±0.3)、(5.0±0.7)mmol/L(P<0.05)。结论芪明颗粒治疗早期糖尿病肾病临床效果显著,值得临床上推广。
Objective To investigate the clinical effect of Qijing granule on early diabetic nephropathy. Methods 76 patients with early diabetic nephropathy were randomly divided into control group and observation group, 38 cases in each. Control group using conventional treatment, the observation group using conventional treatment combined with stilbene particles treatment. The clinical effects of two groups were observed. Results After treatment, the edema score, urine volume, blood urea nitrogen (BUN) and creatinine (Cr) in the observation group were all better than those in the control group (P <0.05). After treatment, the fasting blood glucose (FBG) LDL-C was (4.3 ± 0.4) mmol / L, triglyceride (TG) was (2.7 ± 0.7) mmol / L and total cholesterol was (5.8 ± 0.8) mmol / L, respectively, which were significantly higher than that of the control group (6.2 ± 0.9), (3.4 ± 0.5), (1.8 ± 0.3) and (5.0 ± 0.7) mmol / L, respectively. Conclusion Astragalus Granules treatment of early diabetic nephropathy clinically significant effect, it is worth clinical promotion.