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目的观察分析新生儿寒冷损伤综合征应用小剂量肝素治疗的临床效果。方法 90例新生儿寒冷损伤综合征患儿,通过双色球随机分组法分为观察组和对照组,各45例。对照组患儿实施常规综合性治疗,观察组患儿在此基础上给予小剂量肝素治疗,对两组患儿临床治疗效果进行评价。结果观察组患儿治疗总有效率为93.33%,显著优于对照组的77.78%,差异具有统计学意义(P<0.05);观察组患儿精神反应差、吃奶差、低体温、尿量减少、皮肤硬肿症状恢复时间明显短于对照组(P<0.05)。结论针对新生儿寒冷损伤综合征静脉滴注小剂量肝素,有利于缓解临床症状,提高治疗效果,促进新生儿健康成长,值得临床推广应用。
Objective To observe and analyze the clinical effect of low dose heparin treatment in neonatal cold injury syndrome. Methods A total of 90 neonates with cold injury syndrome were divided into observation group and control group by the method of two-color ball randomization and each group had 45 cases. The control group of children with conventional comprehensive treatment, the observation group of children on the basis of this small dose of heparin treatment, the clinical efficacy of two groups of children were evaluated. Results The total effective rate of treatment group was 93.33%, which was significantly better than that of the control group (77.78%), the difference was statistically significant (P <0.05); poor mental response, poor feeding, hypothermia and urine output Reduce the recovery time of symptoms of skin sclerosis was significantly shorter than the control group (P <0.05). Conclusions The intravenous drip of low dose heparin in neonatal cold injury syndrome is beneficial to relieve clinical symptoms, improve the therapeutic effect and promote the healthy growth of neonates, which is worthy of clinical application.