Thalomid可减缓多发性骨髓瘤的进展

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Celgene公司1月9日宣布,药物沙利度胺(thalidomide, Thalomid)的关键期研究提前终止,因为实验显示该药可显著抑制多发性骨髓瘤的进展。由270例患者参加的Ⅲ期研究显示,以前未治疗过的患者联合使用沙利度胺和地塞米松,其多发性骨髓瘤的进展平均为75.7周,而使用地塞米松单药治疗的患者为27.9周。因 Celgene announced January 9 that the pivotal phase study of thalidomide (Thalomid) was prematurely terminated as experiments show that the drug significantly inhibits the progression of multiple myeloma. A Phase III study of 270 patients showed that in patients with previously untreated thalidomide combined with dexamethasone, the progression of multiple myeloma averaged 75.7 weeks, whereas dexamethasone monotherapy Of patients were 27.9 weeks. because
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