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分枝杆枝菌感染所致的肾衰是不常见的。据报导,在欧洲仅有1%的这种病人需行肾移植治疗。结核性肾衰通常是由于慢性肾实质干酷性坏死和/或纤维化使泌尿道阻塞所致。85%的病人有典型的异常X线表现,并可从尿中培养出结核分杆菌。 1981年,Mallinson等描述了3例间质性肾结核(TIN)病人(2例亚洲人,1例非洲裔加勒比人),未发现有阻塞、集合系统畸形和钙化。3例均接受了适当的抗痨化疗,仅一例采用肾上腺皮质激素治疗者肾功能得到改善,随后该小组又进一步报导了3例TIN病人,包括一例年龄较大的盎格鲁——撒克逊人,再次强调了类固醇治疗的明显益处。所描述的6例病人中,3例显示有结核症状,如夜间盗汗和体重下降;2例病人胸部x线异常,痰检或支气管灌洗液检查菌阳性;有1例患结核性腹膜炎。然而,另3例无结核感染症状。6例病人中5
Renal failure due to mycobacteria mycobacterial infection is uncommon. It has been reported that only 1% of these patients in Europe require kidney transplantation. Tuberculous renal failure is usually due to obstruction of the urinary tract due to chronic renal necrosis and / or fibrosis. Eighty-five percent of patients have typical abnormal X-ray findings and can develop Mycobacterium tuberculosis from urine. In 1981, Mallinson et al. Described 3 patients with interstitial renal tuberculosis (TIN) (2 Asians, 1 African American Caribbean), no obstruction, collection system deformity, and calcification. Three patients received appropriate anti-tuberculosis chemotherapy, and only one patient with adrenal cortex hormones improved renal function. The team then further reported three patients with TIN, including an older Anglo-Saxon, again emphasizing The obvious benefits of steroid therapy. Of the 6 patients described, 3 showed tuberculosis symptoms, such as night sweats and weight loss at night; 2 patients had chest x-ray abnormalities, sputum tests or bronchoalveolar lavage fluid tests; 1 had tuberculous peritonitis. However, the other three had no symptoms of tuberculosis. 6 cases of patients 5