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目的 探讨血清蛋白质脂蛋白[LP(a)]、C反应蛋白(CRP)对颈动脉易损斑块的诊断价值.方法 选取128例伴有颈动脉粥样硬化斑块的急性脑梗死患者,依据彩色多普勒超声检测结果,按斑块性质分为易损斑块组(90例)和稳定斑块组(38例),分别检测2组LP(a)和CRP水平.结果 易损斑块组LP(a)、CRP水平均明显高于稳定斑块组,差异有统计学意义(P<0.01).结论 高水平的血清LP(a)和CRP提示可能存在稳定斑块向易损斑块的转变.“,”Objective To investigate the diagnostic value of serum LP ( a) and C-reactive protein ( CRP) in patients with ca-rotid atherosclerosis vulnerable plaque .Methods One hundred and twenty-eight patients with acute cerebral infarction coupled with carotid atherosclerosis were selected for the study , and they were divided into the vulnerable plaque group (90 cases) and the stable plaque group(38 cases) in accordance with the detection results from color Doppler ultrasonorgraphy .Then, the levels of LP(a) and CRP in the two groups were measured .Results The levels of LP(a) and CRP in the vulnerable plaque group were significantly higher than those in the stable plaque group , and statistical significance could be seen , when comparisons were made between the 2 groups ( P<0.01).Conclusion The higher levels of LP(a) and CRP might indicate that there was probably a transfer from the stable plaque to the vulnerable plaque .