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为评价开展麻疹疫苗 (MV)强化免疫等加速麻疹控制措施的效果 ,分别在加速麻疹控制前后随机选择 11个县和 8个县开展健康人群麻疹抗体水平监测 ,用血凝抑制 (HI)试验检测麻疹抗体。结果表明 :加速麻疹控制后 1～2 9岁健康人群麻疹抗体阳性率由加速麻疹控制前的 92 96 %上升到 96 5 8% ,抗体几何平均滴度倒数 (GMRT)由18 11上升到 2 5 18;加速麻疹控制前 ,3～ 14岁人群麻疹抗体的GMRT随年龄的增长而降低 ,加速麻疹控制后 ,除3岁和≥ 15岁人群外 ,其余年龄组人群的GMRT均显著高于加速麻疹控制前 ,但 3岁GMRT仍最低 ;男女性别之间麻疹抗体阳性率和GMRT差异均无显著的统计学意义 (P >0 0 5 ) ;加速麻疹控制前后 ,均有部分县GMRT处于较低水平。开展MV强化免疫和加强MV的复种能迅速提高相应人群的抗体水平 ,是有效控制麻疹的措施 ,建议在 1 5～ 3岁儿童中增加接种 1剂MV ,加强麻疹血清流行病学监测 ,预防薄弱地区和薄弱人群中麻疹爆发。
To evaluate the effects of measles-control measures such as boosting of measles vaccine (MV), 11 and 8 counties were randomly selected before and after measles control to monitor the measles antibody levels of healthy people and tested by the hemagglutination inhibition (HI) test Measles antibody. The results showed that the measles antibody positive rate of healthy population aged 1 ~ 29 years after measles rash control increased from 92 96% before accelerating measles control to 96 58%, and the geometric mean antibody titer reciprocal (GMRT) increased from 18 11 to 25 GMRT of measles antibody in people aged 3 ~ 14 before accelerated measles control decreased with age. After accelerated measles control, the GMRT of other age groups were significantly higher than that of accelerated measles However, the GMRT at 3 years old was still the lowest before the control. There was no significant difference in the positive rates of GMRT and GMRT between the sexes (P> 0.05). Before and after the accelerated measles control, GMRT was lower in some counties . Carrying out MV boosting and boosting MV vaccination can rapidly increase the antibody level of the corresponding population, which is an effective measure to control measles. It is suggested that one MV be given to children aged 15-3 years to strengthen the monitoring of measles serum epidemiology and prevent weakness. Measles outbreaks in areas and vulnerable populations.