凝血酶系将血纤维蛋白原转化为血纤维蛋白等在血液凝固过程最终阶段起重要作用的蛋白分解酶,最近,为了产生直接止血效果,广泛用作对上消化道出血的局部止血剂。然而,凝血酶原有制剂为小玻璃瓶,易被误认为是注射剂而由血管内给药。日本持田制药公司为防止错误使用,开 Thrombin is a proteolytic enzyme that converts fibrinogen to fibrin and plays an important role in the final stage of blood coagulation. Recently, it has been widely used as a topical hemostatic agent for upper gastrointestinal bleeding in order to produce direct hemostatic effects. However, prothrombin preparations are vials that are easily misinterpreted as injectables for intravascular administration. Japan’s Tian Pharmaceutical Company to prevent the wrong use, open