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虽然急性肾小管坏死是导致急性肾功能衰竭(ARF)的主要原因,肾小球疾病引起的ARF也非少见.有报道其发生率占之25.8%,仅次于急性肾小管坏死.此类疾病预后险恶,但随着近年来治疗学的进展,大部分患者的肾功能于治疗后好转.早期诊断、及时治疗常可改变疾病的病程预后. 一、引起ARF的肾小球疾病各种急进性肾小球肾炎(RPGN)均可导致ARF(附表).患者常于数日或数月内发展为肾功能衰竭、出现少尿.病理上以广泛新月体形成为特点.但有些患者即使在病程早期只有25%的肾小球出现新月体,病情也可急剧发展.国外报
Although acute tubular necrosis is a major cause of acute renal failure (ARF), glomerular disease-causing ARF is also uncommon, with a reported incidence of 25.8%, second only to acute tubular necrosis. Prognosis is sinister, but with the progress of the treatment in recent years, most patients with renal function improved after treatment.Early diagnosis and timely treatment can often change the course of the disease prognosis.Acute glomerular disease caused by ARF Renal glomerulonephritis (RPGN) can cause ARF (Schedule). Patients often develop renal failure within a few days or months with oliguria. Pathological features of extensive crescent formation, but some patients even in the Only 25% of glomeruli in the early course of the disease appear crescent, the condition can also be rapid development.