论文部分内容阅读
目的分析埃可病毒30型(Echo 30)病毒感染的排毒期、危险因素等流行病学特征。方法病例对照研究采用条件Logistic回归分析;实验室检测方法采用病毒逆转录-聚合酶链反应(RT-PCR)检测及序列分析。结果 103例病例中实验室诊断病例30人,男女性别比为2.0:1;年龄范围6~15岁。主要临床症状为发热(100%)、头痛(71.84%)、呕吐(67.00%)、头晕(39.80%)、恶心(33.00%)等。病人密切接触史(OR=5.97,95%CI:1.50~23.86)和喝水龙头生水(OR=4.13,95%CI:1.13~15.04)是病毒感染的危险因素;饭前便后常洗手(OR=0.10,95%CI:0.02~0.37)是保护因素。病例排毒时间7~31天,中位数是10天,平均14天。结论不良饮水习惯和与患者接触是学校Echo 30感染的主要危险因素,饭前便后常洗手可降低感染风险;Echo 30病毒感染患者排毒期为7~31天。
Objective To analyze the epidemiological characteristics of detoxification and risk factors of Echo 30 virus infection. Methods Case-control study using conditional Logistic regression analysis; laboratory testing methods using viral reverse transcription-polymerase chain reaction (RT-PCR) detection and sequence analysis. Results A total of 103 laboratory diagnosed cases were found in 103 cases, with a male-female ratio of 2.0: 1 and an age range of 6-15 years. The main clinical symptoms were fever (100%), headache (71.84%), vomiting (67.00%), dizziness (39.80%) and nausea (33.00%). The close contact history of patients (OR = 5.97, 95% CI: 1.50-23.86) and tap water (OR = 4.13, 95% CI: 1.13-15.04) were the risk factors of virus infection. = 0.10, 95% CI: 0.02 to 0.37) is a protective factor. Case detoxification time 7 to 31 days, the median is 10 days, an average of 14 days. Conclusions Poor drinking water and contact with patients are the main risk factors for Echo 30 infection in schools. Washing hands frequently before and after meals can reduce the risk of infection. Echo 30 virus infection patients with detoxification period of 7 to 31 days.