论文部分内容阅读
选用16例病理学证实的大肠癌患者，手术中抽取患者肠系膜动脉血（A），并分别抽取大肠癌处回流静脉血（C）及邻近正常大肠的系膜静脉血（E），用氨基酸自动分析仪测定A、C、E中游离氨基酸浓度，再将各种氨基酸浓度换算成大肠癌区域动静脉血氨基酸提取率（R1）及正常大肠组织区域动静脉血氨基酸摄取率（R2）。结果：（1）大肠癌区域动静脉血氨基酸提取率明显大于正常大肠区域动静脉血氨基酸提取率（P＜0．01）。（2）大肠癌区域动静脉血氨基酸提取率与肿瘤大小关系不明显，与分期关系不大（仅MET的P＜0．05）。
16 patients with pathologically confirmed colorectal cancer were selected. Mesenteric arterial blood (A) was taken during surgery, and reflux venous blood (C) at the large intestine and mesenteric venous blood (E) adjacent to the normal large intestine were collected. The analyzer measures the concentration of free amino acids in A, C, and E, and then converts each amino acid concentration to amino acid extraction rate (R1) of arteriovenous blood in colorectal cancer regions and amino acid uptake rate (R2) of arteriovenous blood in normal colorectal tissue regions. Results: (1) The amino acid extraction rate of arteriovenous blood in colorectal cancer was significantly higher than that in normal colorectal region (P<0.01). (2) The amino acid extraction rate of arteriovenous blood in colorectal cancer was not significantly related to the tumor size, and it was not related to the stage (P < 0.05 for MET alone).