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[目的]探讨MSCT对中央型未分化小细胞肺癌的诊断价值。[方法]收集2003年1月~2009年9月的经手术或活检病理确诊的21例中央型未分化小细胞肺癌(1组)的MSCT平扫、动态增强资料,与同期80例病理确诊的中央型鳞癌(2组)的MSCT资料进行对比,从中找出有鉴别诊断价值的征象。[结果]在MSCT征象中,1组肿瘤的受累支气管管壁光滑(或不规则)伴支气管通畅的狭窄的出现率、肿瘤长轴方向与相应支气管走行一致的出现率以及肿瘤转移到上腔静脉后、主动脉弓下、隆突下淋巴结的几率明显高于2组,而2组的受累支气管截断或支气管内息肉样结节的出现率、较大肿瘤边缘牵拉邻近叶裂出现的局部结节状突起的出现率以及肿瘤坏死面积与最大横截面积之比明显大于1组(P﹤0.05)。两组间肿瘤阻塞性炎症的发生率差异无统计学意义(P﹥0.05)。1组肿瘤远处转移率大于2组(P﹤0.05)。[结论]MSCT征象有助于中央型未分化细胞癌的诊断及鉴别诊断。
[Objective] To investigate the diagnostic value of MSCT in central undifferentiated small cell lung cancer. [Methods] Twenty-one cases of central undifferentiated small cell lung cancer (group 1) diagnosed by surgery or biopsy from January 2003 to September 2009 were analyzed by MSCT and dynamic contrast-enhanced data. Compared with the 80 cases confirmed by pathology in the same period Central squamous cell carcinoma (two groups) of MSCT data were compared to find the differential diagnosis of signs. [Results] In the MSCT signs, the incidence of smooth (or irregular) bronchial wall involvement in one group of tumors with bronchial patency, the coincidence of the long axis of the tumor with the corresponding bronchial lineage, and the metastasis of tumors to the superior vena cava After the aortic arch, the suboccipital lymph nodes was significantly higher than the 2 groups, and 2 groups of bronchial truncus or bronchial polyp-like nodules, the larger edge of the tumor adjacent to the emergence of lobular local nodules The incidence of protrusion and the ratio of tumor necrosis area to maximum cross-sectional area were significantly larger than those in group 1 (P <0.05). There was no significant difference in the incidence of tumor obstructive inflammation between the two groups (P> 0.05). The distant metastasis rate of tumor in group 1 was higher than that in group 2 (P <0.05). [Conclusion] The signs of MSCT are helpful to the diagnosis and differential diagnosis of central undifferentiated cell carcinoma.