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目的：探讨血清 Ｃ Ａ１２５ 测定及宫腔声学造影诊断子宫腺肌病的价值。方法：对经术后病理检查证实的３１ 例子宫腺肌病（ 腺肌病组） 和２９ 例子宫肌瘤（ 肌瘤组） 患者，术前采用免疫放射法测定血清 Ｃ Ａ１２５ 水平， 并用３ ％ 双氧水行宫腔声学造影检查。１２ 例正常妇女为正常对照组。结果：三组血清 Ｃ Ａ１２５ 阳性率分别为８７ ．１ ％ 、１０ ．３ ％ 、８ ．３ ％ ，均值（ 珋ｘ ±ｓ） 分别为１０５ ．７１ ±６８ ．８２ｋ Ｕ／ Ｌ、１３ ．１４ ±１２ ．９９ｋ Ｕ／ Ｌ、１１ ．８３ ±９ ．９１ｋ Ｕ／ Ｌ。腺肌 病组 Ｃ Ａ１２５ 阳性 率及均值均 明显高于 其他两 组（ Ｐ＜ ０ ．０１） 。宫腔双氧水造影显示，２４ 例腺肌病病人阳性率为７７ ．４２ ％ ， 而肌瘤组和对照组均为阴性结果。两种方法结合分析， 敏感性可提高至９６ ．７７ ％ ， 准确性提高至９３ ．０５ ％ 。结论：血清 Ｃ Ａ１２５ 测定及宫腔双氧水造影对于子宫腺肌病有辅助诊断价值，两者结合应用，能提高诊断的准确性。
Objective: To investigate the value of serum C A125 and intrauterine acoustics in the diagnosis of adenomyosis. Methods: Thirty-one cases of adenomyosis (adenomyosis group) and 29 cases of uterine fibroids (myoma group) confirmed by postoperative pathological examination were enrolled in this study. Serum C A125 levels were measured preoperatively by radioimmunoassay and pretreated with 3% Hypoxia line intrauterine ultrasound imaging. Twelve normal women were normal control group. Results: The positive rates of serum C A125 in the three groups were 87. 1%, 10. 3%, 8. 3%, mean (珋 x ± s) were 105. 71 ± 68. 82k U / L, 13. 14 ± 12. 99k U / L, 11. 83 ± 9. 91k U / L. The positive rate and mean value of C A125 in adenomyosis group were significantly higher than those in the other two groups (P <0.01). Intrauterine hydrogen peroxide imaging showed that 24 cases of adenomyosis patients positive rate of 77. 42%, while the fibroid group and the control group were negative results. Combined analysis of the two methods, the sensitivity can be increased to 96. 77%, accuracy increased to 93. 05%. Conclusion: Serum C A125 determination and uterine cavity hydrogen peroxide in the diagnosis of adenomyosis have auxiliary diagnostic value, the combination of the two can improve the diagnostic accuracy.