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目的探讨认知行为治疗联合药物治疗与单纯药物治疗对肠易激综合征患者生活质量的影响。方法选择2014年10月~2016年10月期间在青岛市海慈医院消化内科就诊的80例腹泻型肠易激综合征(IBS)患者,随机分为两组,研究组41例,对照组39例,对照组患者给予匹维溴铵+帕罗西汀治疗,观察组患者在此基础上联合应用认知行为治疗,疗程8周。分别于治疗前后进行IBS症状严重程度量表(IBS-SSS)、IBS生活质量量表(IBS-QOL)、焦虑自评量表(SAS)、抑郁自评量表(SDS)评定。结果治疗后,两组患者IBS-SSS,IBSQOL,SAS,SDS评分与治疗前均有显著差异;研究组IBS-SSS,SAS,SDS评分明显低于对照组,IBS-QOL评分显著高于对照组,差异均有统计学意义(P<0.05)。结论 IBS患者焦虑抑郁情绪明显,认知行为治疗合并抗抑郁药、常规治疗可进一步提高临床疗效,促进心理健康,改善患者的生活质量。
Objective To explore the impact of cognitive behavioral therapy combined with drug therapy and simple drug therapy on the quality of life in patients with irritable bowel syndrome. Methods Eighty patients with diarrhea-predominant irritable bowel syndrome (IBS) treated in Department of Gastroenterology, Haitai Hospital, Qingdao City from October 2014 to October 2016 were randomly divided into two groups: study group (41 cases), control group (39 cases) For example, patients in the control group were treated with piroxicam and paroxetine. Patients in the observation group were treated with cognitive behavioral therapy on the basis of the above, and the course of treatment was 8 weeks. The IBS-SSS, IBS-QOL, SAS and SDS were assessed before and after treatment. Results After treatment, IBS-SSS, IBSQOL, SAS, SDS scores of both groups were significantly different from those before treatment; IBS-SSS, SAS and SDS scores of the study group were significantly lower than those of the control group, IBS-QOL score was significantly higher than the control group , The differences were statistically significant (P <0.05). Conclusions Patients with IBS have significant anxiety and depression feelings and cognitive behavioral therapy with antidepressants. Conventional treatment can further improve clinical efficacy, promote mental health and improve patients’ quality of life.