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目的探讨保乳手术治疗高龄乳腺癌患者的临床疗效。方法 120例Ⅰ期和Ⅱ期乳腺癌患者随机分为观察组和对照组,每组各60例,观察组采用保乳手术,对照组采用改良根治术,术后均给予辅助放化疗和内分泌治疗,比较两组的围手术期指标、生存率、美容效果满意度和生活质量。结果观察组患者的术中出血量、引流量、手术时间和拔管时间均明显少于对照组(P<0.05);观察组美容效果的优良率为90.0%,显著高于对照组的71.7%(P<0.05),术后两组患者的生存率无明显差别;观察组的角色功能、社会功能和总体健康状况明显优于对照组(P<0.05)。结论保乳手术治疗高龄乳腺癌患者具有良好的效果,可以提高患者的美容效果和生活质量,值得在临床推广。
Objective To investigate the clinical efficacy of breast-conserving surgery for elderly patients with breast cancer. Methods A total of 120 patients with stage I and II breast cancer were randomly divided into observation group and control group, with 60 cases in each group. The observation group received conservative surgery and the control group received modified radical mastectomy. Adjuvant radiochemotherapy and endocrine therapy The perioperative indexes, survival rate, cosmetic satisfaction and quality of life were compared between the two groups. Results The blood loss, drainage, operation time and extubation time in the observation group were significantly less than those in the control group (P <0.05). The excellent and good rate of the cosmetic effect in the observation group was 90.0%, significantly higher than that of the control group (71.7% (P <0.05). There was no significant difference in survival rate between the two groups after operation. The role function, social function and general health of the observation group were significantly better than those of the control group (P <0.05). Conclusion Breast-conserving surgery for elderly patients with breast cancer has a good effect, can improve the patient’s cosmetic effect and quality of life, it is worth in the clinical promotion.