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目的:探讨肌钙蛋白I、CKMB的即时检测技术在急诊科心肌梗死患者中的应用及其临床意义。方法:研究对象为2012年10月至2013年8月于我急诊科急诊的急性心肌梗死患者,按就诊时间分为对照组和实验组。对照组患者采用常规化验室检测肌钙蛋白I、CKMB,实验组采用急诊科即时检测方法检测肌钙蛋白I、CKMB。对比两组患者从就诊到确诊的时间、住院天数、治愈率、心功能不全发生率和死亡率。结果:实验组患者的确诊时间为(25.5±5.6)min,住院天数为(9.89±1.5)天,治愈率为80.8%,心功能不全发生率为15.4%。对照组患者的确诊时间为(66.8±10.0)min,住院天数为(12.6±2.5)天,治愈率为56.0%,心功能不全发生率为32.0%P均<.0.05,有统计学意义。两组患者死亡率分别为12%和3.8%,无明显差异。结论:对心肌梗死患者采用肌钙蛋白I、CKMB的即时检测对于提高患者治愈率,减少确诊时间和住院时间,降低心功能不全发生率有很大帮助。
Objective: To investigate the application of real-time detection of troponin I and CKMB in patients with acute myocardial infarction and its clinical significance. Methods: The subjects were acute myocardial infarction patients in our emergency department from October 2012 to August 2013. The patients were divided into control group and experimental group according to the visiting time. Patients in the control group were tested for troponin I and CKMB by routine laboratory tests, and cardiac troponin I and CKMB were detected by real-time emergency department in the experimental group. Comparing the two groups from the time of diagnosis to treatment, hospitalization days, cure rate, heart failure rate and mortality. Results: The experimental group had a definite diagnosis time of (25.5 ± 5.6) min, a hospitalization day of (9.89 ± 1.5) days, a cure rate of 80.8% and a cardiac dysfunction rate of 15.4%. The patients in the control group had a definite diagnosis time of (66.8 ± 10.0) min, a hospitalization day of (12.6 ± 2.5) days, a cure rate of 56.0% and a cardiac dysfunction rate of 32.0% (all P <0.05), with statistical significance. Mortality rates in both groups were 12% and 3.8%, respectively, with no significant difference. Conclusion: The real-time detection of cardiac troponin I and CKMB in patients with myocardial infarction is very helpful to improve the cure rate, reduce the time of diagnosis and hospital stay, and reduce the incidence of cardiac dysfunction.