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目的 探讨胃癌并幽门梗阻时TNM 分期的临床特点,以指导诊治及判断预后。方法 按国际抗癌联盟TNM 分期及补充规则,对108 例胃癌并幽门梗阻进行临床分析。结果 T4 N2 M1 病例占66-6% ,早、中期胃癌梗阻时间平均11-4 天,晚期胃癌梗阻50-4 天,差异有非常显著意义( P< 0-01) 。上腹扪及肿块48 例,其中47 例为Ⅳ期,另1 例为Ⅲb 期。结论 胃癌并幽门梗阻绝大部分为癌症晚期。幽门梗阻可能促进胃癌发展,时间越长,越有可能发展至晚期。胃癌并幽门梗阻超过1 个月,或上腹扪及肿块者,绝大部分为胃癌晚期病人,可作为临床诊断分期指标之一。宜早期手术,解除梗阻。
Objective To investigate the clinical features of TNM staging in gastric cancer with pyloric obstruction to guide diagnosis and treatment and determine prognosis. Methods Clinical analysis of 108 cases of gastric cancer with pyloric obstruction was performed according to the TNM staging and supplementary rules of the International Union Against Cancer. Results The T4 N2 M1 cases accounted for 66-6%. The early and middle gastric cancer obstruction time was 11-4 days on average, and the advanced gastric cancer obstruction was 50-4 days. The difference was very significant (P < 0-01). There were 48 epigastric fistulas and masses, of which 47 were stage IV and the other was stage IIIb. Conclusion The majority of gastric cancer with pyloric obstruction is late stage cancer. Pyloric obstruction may promote the development of gastric cancer. The longer the time is, the more likely it is to develop to late stage. More than 1 month of gastric cancer with pyloric obstruction, or abdominal hernia and mass, the vast majority of patients with advanced gastric cancer, can be used as one of the clinical diagnostic staging indicators. Should be early surgery to relieve obstruction.